Programmatic discovery

Top cited papers, continuously indexable.

This page pulls one slice of the highest-cited DOI-backed works from OpenAlex and links every result to its branded resea.org DOI page. It exists to create crawl paths, not just a single vanity landing.

Primer3—new capabilities and interfaces

9834 citations2012Nucleic Acids Research
Andreas Untergasser, Ioana Cutcutache, Triinu Kõressaar, Jian Ye, Brant C. Faircloth

Polymerase chain reaction (PCR) is a basic molecular biology technique with a multiplicity of uses, including deoxyribonucleic acid cloning and sequencing, functional analysis of genes, diagnosis of diseases, genotyping…

Supramolecular Chemistry

9825 citations1995Unknown source
J.-M. Lehn

Part 1 From molecular to supramolecular chemistry: concepts and language of supramolecular chemistry. Part 2 Molecular recognition: recognition, information, complementarity molecular receptors - design principles spher…

Textbook of Medical Physiology

9818 citations1966Annals of Internal Medicine
Guyton,Arthur C, Hall, John E

This is a comprehensive yet concise edition geared toward medical and dental students enrolled in physiology courses. The textbook also serves as a review resource for physiology instructors. It offers specific discussi…

Learning from Imbalanced Data

9806 citations2009IEEE Transactions on Knowledge and Data Engineering
Haibo He, Edwardo A. Garcia

With the continuous expansion of data availability in many large-scale, complex, and networked systems, such as surveillance, security, Internet, and finance, it becomes critical to advance the fundamental understanding…

Enriching Word Vectors with Subword Information

9805 citations2017Transactions of the Association for Computational Linguistics
Piotr Bojanowski, Édouard Grave, Armand Joulin, Tomáš Mikolov

Continuous word representations, trained on large unlabeled corpora are useful for many natural language processing tasks. Popular models that learn such representations ignore the morphology of words, by assigning a di…

<i>The Physics of Liquid Crystals</i>

9798 citations1995Physics Today
P. G. de Gennes, Jacques Prost, Robert A. Pelcovits

Part 1 Liquid crystals - main types and properties: introduction - what is a liquid crystal? the building blocks nematics and cholesterics smectics columnar phases more on long-, quasi-long and short-range order remarka…

Clathrate Hydrates of Natural Gases

9796 citations2007Unknown source
E. Dendy Sloan, Carolyn A. Koh, Carolyn A. Koh

Hydrate research has expanded substantially over the past decade, resulting in more than 4,000 hydrate-related publications. Collating this vast amount of information into one source, Clathrate Hydrates of Natural Gases…

Selections from the prison notebooks

9791 citations2020Unknown source
Antonio Gramsci

When one distinguishes between intellectuals and non intellectuals, one is referring in reality only to the immediate social function of the professional category of the intellectuals, that is, one has in mind the direc…

The Economics of Climate Change: The Stern Review

9783 citations2007London School of Economics and Political Science Research Online (London School of Economics and Political Science)
Nicholas Stern

There is now clear scientific evidence that emissions from economic activity, particularly the burning of fossil fuels for energy, are causing changes to the Earth´s climate. A sound understanding of the economics of cl…

A Short Physical Performance Battery Assessing Lower Extremity Function: Association With Self-Reported Disability and Prediction of Mortality and Nursing Home Admission

9755 citations1994Journal of Gerontology
Jack M. Guralnik, E. M. Simonsick, Luigi Ferrucci, Robert J. Glynn, Lisa Berkman

BACKGROUND: A short battery of physical performance tests was used to assess lower extremity function in more than 5,000 persons age 71 years and older in three communities. METHODS: Balance, gait, strength, and enduran…

ColabFold: making protein folding accessible to all

9755 citations2022Nature Methods
Milot Mirdita, Konstantin Schütze, Yoshitaka Moriwaki, Lim Heo, Sergey Ovchinnikov

ColabFold offers accelerated prediction of protein structures and complexes by combining the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40-60-fold faster search and optimized model utili…

The Li-Ion Rechargeable Battery: A Perspective

9755 citations2013Journal of the American Chemical Society
John B. Goodenough, Kyu‐Sung Park

Each cell of a battery stores electrical energy as chemical energy in two electrodes, a reductant (anode) and an oxidant (cathode), separated by an electrolyte that transfers the ionic component of the chemical reaction…

Vision meets robotics: The KITTI dataset

9748 citations2013The International Journal of Robotics Research
Andreas Geiger, Philip Lenz, Christoph Stiller, Raquel Urtasun

We present a novel dataset captured from a VW station wagon for use in mobile robotics and autonomous driving research. In total, we recorded 6 hours of traffic scenarios at 10–100 Hz using a variety of sensor modalitie…

A Mathematical Theory of Communication

9744 citations1948Bell System Technical Journal
Claude E. Shannon

In this final installment of the paper we consider the case where the signals or the messages or both are continuously variable, in contrast with the discrete nature assumed until now. To a considerable extent the conti…

The integrative review: updated methodology

9742 citations2005Journal of Advanced Nursing
Robin Whittemore, Kathleen A. Knafl

AIM: The aim of this paper is to distinguish the integrative review method from other review methods and to propose methodological strategies specific to the integrative review method to enhance the rigour of the proces…

Surviving Sepsis Campaign

9735 citations2013Critical Care Medicine
R. Phillip Dellinger, Mitchell M. Levy, Andrew Rhodes, Djillali Annane, Herwig Gerlach

To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008. A consensus committee of 68 international experts representing 30 internationa…

Cancer Statistics, 2009

9725 citations2009CA A Cancer Journal for Clinicians
Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward, Yongping Hao, Jianfeng Xu

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival…

Cognitive Therapy for Depression

9719 citations2012PsycEXTRA Dataset

We provide an overview of cognitive therapy (CT) of depression, including its treatment procedures, therapeutic effects, and mechanisms of change, as well as its effectiveness and dissemination. CT is a well-established…

Inference and missing data

9711 citations1976Biometrika
Donald B. Rubin

When making sampling distribution inferences about the parameter of the data, θ, it is appropriate to ignore the process that causes missing data if the missing data are ‘missing at random’ and the observed data are ‘ob…

A Self-Rating Depression Scale

9706 citations1965Archives of General Psychiatry
William W.K. Zung

The fact that there is a need for assessing depression, whether as an affect, a symptom, or a disorder is obvious by the numerous scales and inventories available and in use today. The need to assess depression simply a…

The Physical Activity Guidelines for Americans

9703 citations2018JAMA
Katrina L. Piercy, Richard P. Troiano, Rachel Ballard, Susan A. Carlson, Janet E. Fulton

Importance: Approximately 80% of US adults and adolescents are insufficiently active. Physical activity fosters normal growth and development and can make people feel, function, and sleep better and reduce risk of many…

The Production of Space

9685 citations1992Economic Geography
E Swyngedouw, Henri Lefebvre

Translatora s Acknowledgements. 1. Plan of the Present Work. 2. Social Space. 3. Spatial Architectonics. 4. From Absolute Space to Abstract Space. 5. Contradictory Space. 6. From the Contradictions of Space to Different…

Chord

9683 citations2001Unknown source
Ion Stoica, Robert Morris, David R. Karger, M. Frans Kaashoek, Hari Balakrishnan

A fundamental problem that confronts peer-to-peer applications is to efficiently locate the node that stores a particular data item. This paper presents Chord, a distributed lookup protocol that addresses this problem.…

Translating the Histone Code

9681 citations2001Science
Thomas Jenuwein, C. David Allis

Chromatin, the physiological template of all eukaryotic genetic information, is subject to a diverse array of posttranslational modifications that largely impinge on histone amino termini, thereby regulating access to t…

A Survey of Augmented Reality

9680 citations1997PRESENCE Virtual and Augmented Reality
Ronald Azuma

This paper surveys the field of augmented reality (AR), in which 3D virtual objects are integrated into a 3D real environment in real time. It describes the medical, manufacturing, visualization, path planning, entertai…

Kinetics of Adsorption on Carbon from Solution

9654 citations1963Journal of the Sanitary Engineering Division
Walter J. Weber, John C. Morris

Laboratory investigations show that rates of adsorption of persistent organic compounds on granular carbon are quite low. Intraparticle diffusion of solute appears to control the rate of uptake, thus the rate is partial…

UMAP: Uniform Manifold Approximation and Projection

9647 citations2018The Journal of Open Source Software
Leland McInnes, John Healy, Nathaniel Saul, Lukas Großberger

Uniform Manifold Approximation and Projection (UMAP) is a dimension reduction technique that can be used for visualisation similarly to t-SNE, but also for general non-linear dimension reduction. UMAP has a rigorous mat…

A Treatise on the Theory of Bessel Functions.

9643 citations1923American Mathematical Monthly
Matthew Porter, G. N. Watson

1. Bessel functions before 1826 2. The Bessel coefficients 3. Bessel functions 4. Differential equations 5. Miscellaneous properties of Bessel functions 6. Integral representations of Bessel functions 7. Asymptotic expa…

A Neural Substrate of Prediction and Reward

9636 citations1997Science
Wolfram Schultz, Peter Dayan, P. Read Montague

The capacity to predict future events permits a creature to detect, model, and manipulate the causal structure of its interactions with its environment. Behavioral experiments suggest that learning is driven by changes…

The Amber biomolecular simulation programs

9625 citations2005Journal of Computational Chemistry
David A. Case, Thomas E. Cheatham, Tom Darden, Holger Gohlke, Ray Luo

We describe the development, current features, and some directions for future development of the Amber package of computer programs. This package evolved from a program that was constructed in the late 1970s to do Assis…

Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

9618 citations2020The Lancet
Christopher J L Murray, Aleksandr Y. Aravkin, Peng Zheng, Cristiana Abbafati, Kaja Abbas

BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cas…