Top cited papers, continuously indexable.

Mental Health and the Covid-19 Pandemic Many aspects of the Covid-19 pandemic and the public health response to it will undoubtedly contribute to widespread emotional distress and increased risk fo...

Most psychologists take it for granted that a scientific account of the behavior of organisms must begin with the definition of fixed, recognizable, elementary units of behavior—something a psychologist can use as a bio…

To revise 1998 recommendations on childhood obesity, an Expert Committee, comprised of representatives from 15 professional organizations, appointed experienced scientists and clinicians to 3 writing groups to review th…

There is growing interest in the possible health threat posed by endocrine-disrupting chemicals (EDCs), which are substances in our environment, food, and consumer products that interfere with hormone biosynthesis, meta…

PURPOSE Neuroendocrine tumors (NETs) are considered rare tumors and can produce a variety of hormones. In this study, we examined the epidemiology of and prognostic factors for NETs, because a thorough examination of ne…

Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue rem…

This classic work chronicles how New York, London, and Tokyo became command centers for the global economy and in the process underwent a series of massive and parallel changes. What distinguishes Sassen's theoretical f…

If model parameterizations of unresolved physics, such as the variety of upper ocean mixing processes, are to hold over the large range of time and space scales of importance to climate, they must be strongly physically…

Optical Properties of Solids covers the important concepts of intrinsic optical properties and photoelectric emission. The book starts by providing an introduction to the fundamental optical spectra of solids. The text…

Abstract. Secondary organic aerosol (SOA) accounts for a significant fraction of ambient tropospheric aerosol and a detailed knowledge of the formation, properties and transformation of SOA is therefore required to eval…

A new approach to the problem of multimodality medical image registration is proposed, using a basic concept from information theory, mutual information (MI), or relative entropy, as a new matching criterion. The method…

A general procedure is introduced for calculation of the electron correlation energy, starting from a single Hartree–Fock determinant. The normal equations of (linear) configuration interaction theory are modified by in…

Detecting and reading text from natural images is a hard computer vision task that is central to a variety of emerging applications. Related problems like document character recognition have been widely studied by compu…

CRISPR-Cas12a (Cpf1) proteins are RNA-guided enzymes that bind and cut DNA as components of bacterial adaptive immune systems. Like CRISPR-Cas9, Cas12a has been harnessed for genome editing on the basis of its ability t…

This paper presents a novel adaptive synthetic (ADASYN) sampling approach for learning from imbalanced data sets. The essential idea of ADASYN is to use a weighted distribution for different minority class examples acco…

Quantile regression is gradually emerging as a unified statistical methodology for estimating models of conditional quantile functions. By complementing the exclusive focus of classical least squares regression on the c…

While supervised learning has enabled great progress in many applications, unsupervised learning has not seen such widespread adoption, and remains an important and challenging endeavor for artificial intelligence. In t…

This review covers several topics involving renormalization group ideas. The solution of the $s$-wave Kondo Hamiltonian, describing a single magnetic impurity in a nonmagnetic metal, is explained in detail. See Secs. VI…

Wir wünschen uns für diese Abhandlung Leser, die zunächst einmal über ihren Arbeitsstoff und Arbeitskreis Bescheid wissen möchten, die sich selbst und anderen aus Wissensdurst Fragen stellen und denen dieses immer mehr…

A third‐generation numerical wave model to compute random, short‐crested waves in coastal regions with shallow water and ambient currents (Simulating Waves Nearshore (SWAN)) has been developed, implemented, and validate…

It is shown that the Hartree-Fock equations can be regarded as ordinary Schr\"odinger equations for the motion of electrons, each electron moving in a slightly different potential field, which is computed by electrostat…

ChEMBL is an Open Data database containing binding, functional and ADMET information for a large number of drug-like bioactive compounds. These data are manually abstracted from the primary published literature on a reg…

BACKGROUND: A worldwide outbreak of severe acute respiratory syndrome (SARS) has been associated with exposures originating from a single ill health care worker from Guangdong Province, China. We conducted studies to id…

The primary aim of this article is to provide an overview of perfluoroalkyl and polyfluoroalkyl substances (PFASs) detected in the environment, wildlife, and humans, and recommend clear, specific, and descriptive termin…

The comparison, made by Dr. W. D. Jeans in your last issue*, of Gray's Anatomy with the latest revision of its American offspring is an interesting exercise; but his conclusion that the original is a ‘better buy’, thoug…

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPartition coefficients and their usesAlbert Leo, Corwin Hansch, and David ElkinsCite this: Chem. Rev. 1971, 71, 6, 525–616Publication Date (Print):December 1, 1971Publication…

Zusammenfassung Ich habe in diesem Aufsatz kurz anzudeuten versucht, was meiner Ansicht nach das Wesentliche in Fragestellung und Methode der Ethologie ist und weshalb wir in Konrad Lorenz den Begründer moderner Etholog…

OBJECTIVE: To evaluate the efficacy and safety of tadalafil monotherapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH). METHODS: A comprehensive search was done to identify randomi…

BACKGROUND: Nosocomial bloodstream infections (BSIs) are important causes of morbidity and mortality in the United States. METHODS: Data from a nationwide, concurrent surveillance study (Surveillance and Control of Path…

The authors address the assumptions and methods that allow us to turn observations into causal knowledge, and use even incomplete causal knowledge in planning and prediction to influence and control our environment. Wha…

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTControlled/"living" radical polymerization. atom transfer radical polymerization in the presence of transition-metal complexesJin-Shan Wang and Krzysztof MatyjaszewskiCite thi…

Efforts to anticipate how climate change will affect future food availability can benefit from understanding the impacts of changes to date. We found that in the cropping regions and growing seasons of most countries, w…

Mesenchymal stem cells (MSCs) are multipotent cells found in several adult tissues. Transplanted allogeneic MSCs can be detected in recipients at extended time points, indicating a lack of immune recognition and clearan…

BACKGROUND: The availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an evolutionary classification of genes f…

Strong, electromagnetic, and weak forces are conjectured to arise from a single fundamental interaction based on the gauge group SU(5).Received 10 January 1974DOI:https://doi.org/10.1103/PhysRevLett.32.438©1974 American…

The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The…

Drawing on the correspondence between the graph Laplacian, the Laplace-Beltrami operator on a manifold, and the connections to the heat equation, we propose a geometrically motivated algorithm for constructing a represe…

CONTEXT: Interstitial radiation (implant) therapy is used to treat clinically localized adenocarcinoma of the prostate, but how it compares with other treatments is not known. OBJECTIVE: To estimate control of prostate-…

Much of the prior research on interorganizational learning has focused on the role of absorptive capacity, a firm's ability to value, assimilate, and utilize new external knowledge. However, this definition of the const…

A novel method for differentiating between correctly and incorrectly determined regions of protein structures based on characteristic atomic interaction is described. Different types of atoms are distributed nonrandomly…

This paper describes a generalization of the inverse of a non-singular matrix, as the unique solution of a certain set of equations. This generalized inverse exists for any (possibly rectangular) matrix whatsoever with…

This chapter addresses three types of personal communication skills necessary to thrive in the real world outside of school: Email, oral communication, and listening. Each of these skills should be addressed in developm…

1. The most important way to prevent atherosclerotic vascular disease, heart failure, and atrial fibrillation is to promote a healthy lifestyle throughout life. 2. A team-based care approach is an effective strategy for…

A method is proposed, called channel polarization, to construct code sequences that achieve the symmetric capacity$I(W)$of any given binary-input discrete memoryless channel (B-DMC)$W$. The symmetric capacity is the hig…

The Hausdorff distance measures the extent to which each point of a model set lies near some point of an image set and vice versa. Thus, this distance can be used to determine the degree of resemblance between two objec…

The Merck Index is a one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs. Each monograph in this authoritative reference source is a concise description of a single subs…

Three-dimensional failure criteria of unidirectional fiber composites are established in terms of quadratic stress polynomials which are expressed in terms of the transversely isotropic invariants of the applied average…

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLimits for qualitative detection and quantitative determination. Application to radiochemistryLloyd A. CurrieCite this: Anal. Chem. 1968, 40, 3, 586–593Publication Date (Print…

Low-dimensional embeddings of nodes in large graphs have proved extremely useful in a variety of prediction tasks, from content recommendation to identifying protein functions. However, most existing approaches require…

Generative adversarial networks (GANs) provide a way to learn deep representations without extensively annotated training data. They achieve this by deriving backpropagation signals through a competitive process involvi…

Phase transitions are ubiquitous in nonliving matter, and recent discoveries have shown that they also play a key role within living cells. Intracellular liquid-liquid phase separation is thought to drive the formation…

Age-related macular degeneration (AMD) is a major cause of blindness in the elderly. We report a genome-wide screen of 96 cases and 50 controls for polymorphisms associated with AMD. Among 116,204 single-nucleotide poly…

Agent-based modeling is a powerful simulation modeling technique that has seen a number of applications in the last few years, including applications to real-world business problems. After the basic principles of agent-…

Actin purified by a new, simple, and rapid purification procedure activated the ATPase activity of both heavy meromyosin and Subfragment 1 of heavy meromyosin, and this activation was not inhibited by the removal of Ca2…

OBJECTIVE: Despite extensive use of oral anticoagulation (OAC) in patients with atrial fibrillation (AF) and the increased bleeding risk associated with such OAC use, no handy quantification tool for assessing this risk…

New materials capable of storing hydrogen at high gravimetric and volumetric densities are required if hydrogen is to be widely employed as a clean alternative to hydrocarbon fuels in cars and other mobile applications.…

The structure of scientific collaboration networks is investigated. Two scientists are considered connected if they have authored a paper together and explicit networks of such connections are constructed by using data…

Amabile, T. M. (1988). A model of creativity and innovation in organizations. Research in organizational behavior , 10(1), 123-167.

Motivated by the recent explosion of interest around blockchains, we examine whether they make a good fit for the Internet of Things (IoT) sector. Blockchains allow us to have a distributed peer-to-peer network where no…

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTGraphene-Like Two-Dimensional MaterialsMingsheng Xu*, Tao Liang, Minmin Shi, and Hongzheng ChenView Author Information State Key Laboratory of Silicon Materials, MOE Key Labora…

CONTEXT: Survival estimates help individualize goals of care for geriatric patients, but life tables fail to account for the great variability in survival. Physical performance measures, such as gait speed, might help a…

We critically review dissipative particle dynamics (DPD) as a mesoscopic simulation method. We have established useful parameter ranges for simulations, and have made a link between these parameters and χ-parameters in…

Use of high-resolution micro-computed tomography (microCT) imaging to assess trabecular and cortical bone morphology has grown immensely. There are several commercially available microCT systems, each with different app…

Drug delivery systems (DDS) such as lipid- or polymer-based nanoparticles can be designed to improve the pharmacological and therapeutic properties of drugs administered parenterally. Many of the early problems that hin…

The first global assessment of amphibians provides new context for the well-publicized phenomenon of amphibian declines. Amphibians are more threatened and are declining more rapidly than either birds or mammals. Althou…

Principles for reporting analyses using structural equation modeling are reviewed, with the goal of supplying readers with complete and accurate information. It is recommended that every report give a detailed justifica…

Tetracyclines were discovered in the 1940s and exhibited activity against a wide range of microorganisms including gram-positive and gram-negative bacteria, chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites.…