Programmatic discovery

Top cited papers, continuously indexable.

This page pulls one slice of the highest-cited DOI-backed works from OpenAlex and links every result to its branded resea.org DOI page. It exists to create crawl paths, not just a single vanity landing.

Fluorine in medicinal chemistry

7521 citations2007Chemical Society Reviews
Sophie Purser, Peter R. Moore, Steve Swallow, Véronique Gouverneur

It has become evident that fluorinated compounds have a remarkable record in medicinal chemistry and will play a continuing role in providing lead compounds for therapeutic applications. This tutorial review provides a…

Separable dual-space Gaussian pseudopotentials

7521 citations1996Physical review. B, Condensed matter
Stefan Goedecker, M. P. Teter, Jürg Hutter

We present pseudopotential coefficients for the first two rows of the Periodic Table. The pseudopotential is of an analytic form that gives optimal efficiency in numerical calculations using plane waves as a basis set.…

Determining Optical Flow

7494 citations1981Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Berthold K. P. Horn, Brian G. Schunck

Optical flow cannot be computed locally, since only one independent measurement is available from the image sequence at a point, while the flow velocity has two components. A second constraint is needed. A method for fi…

Bad is Stronger than Good

7493 citations2001Review of General Psychology
Roy F. Baumeister, Ellen Bratslavsky, Catrin Finkenauer, Kathleen D. Vohs

The greater power of bad events over good ones is found in everyday events, major life events (e.g., trauma), close relationship outcomes, social network patterns, interpersonal interactions, and learning processes. Bad…

A vector space model for automatic indexing

7490 citations1975Communications of the ACM
Gerard Salton, Anita M.-Y. Wong, Chul‐Su Yang

In a document retrieval, or other pattern matching environment where stored entities (documents) are compared with each other or with incoming patterns (search requests), it appears that the best indexing (property) spa…

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

7489 citations2019Stroke
William J. Powers, Alejandro A. Rabinstein, Teri Ackerson, Opeolu Adeoye, Nicholas C. Bambakidis

Background and Purpose- The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations in a single document for clinicians caring for adult patients with acute arterial ischemic stroke.…

Cancer Statistics, 2007

7486 citations2007CA A Cancer Journal for Clinicians
Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward, Taylor Murray, Jiaquan Xu

Each year, the American Cancer Society (ACS) estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and su…

A semi-empirical method of absorption correction

7484 citations1968Acta Crystallographica Section A
A.C.T. North, D. C. Phillips, F. Scott Mathews

An extension of Furnas's method is described. The variation of intensity of an axial reflection as the crystal is rotated about the goniometer axis is used to give a curve of relative transmission T against azimuthal an…

Black Holes and Entropy

7481 citations1973Physical review. D. Particles, fields, gravitation, and cosmology/Physical review. D. Particles and fields
Jacob D. Bekenstein

There are a number of similarities between black-hole physics and thermodynamics. Most striking is the similarity in the behaviors of black-hole area and of entropy: Both quantities tend to increase irreversibly. In thi…

Bond-valence parameters for solids

7477 citations1991Acta Crystallographica Section B Structural Science
Nathaniel E. Brese, M. O’Keeffe

Bond-valence parameters which relate bond valences and bond lengths have been derived for a large number of bonds. It is shown that there is a strong linear correlation between the parameters for bonds from cations to p…

Improved metagenomic analysis with Kraken 2

7452 citations2019Genome biology
Derrick E. Wood, Jennifer Lu, Ben Langmead

Although Kraken's k-mer-based approach provides a fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reduc…

Review of Particle Physics

7451 citations2016Chinese Physics C
K.A. Olive

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,062 new measurements from 721 papers, we list, evaluate, and average measured properties of gauge bosons and the re…

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

7443 citations2017Hypertension
Paul K. Whelton, Robert M. Carey, Wilbert S. Aronow, Donald E. Casey, Karen J. Collins

Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to improve cardiovascular…

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

7443 citations2016The Lancet
Theo Vos, Christine A. Allen, Megha Arora, Ryan M Barber, Zulfiqar A Bhutta

BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countrie…

Theory of rational option pricing

7440 citations2005WORLD SCIENTIFIC eBooks
Robert C. Merton

AbstractThe following sections are included:IntroductionRestrictions on rational option pricingEffects of dividends and changing exercise priceRestrictions on rational put option oricinaRational option pricing along Bla…

Finite Mixture Models

7427 citations2000Wiley series in probability and statistics
Geoffrey J. McLachlan, Sharon X. Lee, Suren I. Rathnayake

The important role of finite mixture models in the statistical analysis of data is underscored by the ever-increasing rate at which articles on mixture applications appear in the statistical and general scientific liter…

Encyclopedia of Analytical Chemistry

7426 citations2006Unknown source
Grochocki, W, Markuszewski, MJ, Quirino, JP

Correlation between light, mostly fluorescence, and electron microscopy (EM) is needed to identify biological molecules within their ultrastructural context and/or to relate the ultrastructure to preceding dynamics of b…

Electrophilicity Index

7424 citations1999Journal of the American Chemical Society
Robert G. Parr, László von Szentpály, Shubin Liu

Prompted by a recent paper by Maynard and co-workers (Maynard, A. T.; Huang, M.; Rice, W. G.; Covel, D. G. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 11578), we propose that a specific property of a chemical species, the s…

Self-Assembly at All Scales

7418 citations2002Science
George M. Whitesides, Bartosz A. Grzybowski

Self-assembly is the autonomous organization of components into patterns or structures without human intervention. Self-assembling processes are common throughout nature and technology. They involve components from the…

The Wretched of the Earth

7416 citations2000Princeton University Press eBooks
Frantz Fanon

Come, then, comrades; it would be as well to decide at once to change our ways. We must shake off the heavy darkness in which we were plunged, and leave it behind. The new day which is already at hand must find us firm,…

Foundations of Behavioral Research

7416 citations1974American Educational Research Journal
Rex Stockton, Fred N. Kerlinger

First published in 1964, this text has set the standard for other texts in the field of behavioral research methodology. It emphasises the fundamentals of understanding how to solve a scientific research problem, focusi…