DOI resolved by resea

Protein Identification and Analysis Tools on the ExPASy Server

Protein identification and analysis software performs a central role in the investigation of proteins from two-dimensional (2-D) gels and mass spectrometry. For protein identification, the…

Elisabeth Gasteiger, Christine Hoogland, Alexandre Gattiker, Séverine Duvaud, Marc R. Wilkins, Ron D. Appel, Amos Bairoch
https://resea.org/10.1385/1-59259-890-0:571

Abstract

Protein identification and analysis software performs a central role in the investigation of proteins from two-dimensional (2-D) gels and mass spectrometry. For protein identification, the user matches certain empirically acquired information against a protein database to define a protein as already known or as novel. For protein analysis, information in protein databases can be used to predict certain properties about a protein, which can be useful for its empirical investigation. The two processes are thus complementary. Although there are numerous programs available for those applications, we have developed a set of original tools with a few main goals in mind. Specifically, these are: