DOI resolved by resea

A new method for predicting signal sequence cleavage sites

A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accura…

Gunnar von Heijne
https://resea.org/10.1093/nar/14.11.4683

Abstract

A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.