Let the concept of trait be functional!
4680 citations2007Oikos
Cyrille Violle, Marie‐Laure Navas, Denis Vile, Elena Kazakou, Claire Fortunel
In its simplest definition, a trait is a surrogate of organismal performance, and this meaning of the term has been used by evolutionists for a long time. Over the last three decades, developments in community and ecosy…
Geometric Control of Cell Life and Death
4680 citations1997Science
Christopher S. Chen, Milan Mrksich, Sui Huang, George M. Whitesides, Donald E. Ingber
Human and bovine capillary endothelial cells were switched from growth to apoptosis by using micropatterned substrates that contained extracellular matrix-coated adhesive islands of decreasing size to progressively rest…
Incidence of Adverse Events and Negligence in Hospitalized Patients
4680 citations1991New England Journal of Medicine
Troyen A. Brennan, Lucian L. Leape, Nan M. Laird, Liesi E. Hebert, A. Russell Localio
BACKGROUND: As part of an interdisciplinary study of medical injury and malpractice litigation, we estimated the incidence of adverse events, defined as injuries caused by medical management, and of the subgroup of such…
A Monte Carlo computer program for the transport of energetic ions in amorphous targets
4680 citations1980Nuclear Instruments and Methods
J.P. Biersack, L.G. Haggmark
Markets, Bureaucracies, and Clans
4680 citations1980Administrative Science Quarterly
William G. Ouchi
Abstract The issue of successfully coordinating different activities under circumstances of uncertainty and turbulence is one of the most fundamental and most difficult ones for modern logisticians and designers of supp…
Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus
4679 citations2020Journal of Virology
Yushun Wan, Jian Shang, Rachel L. Graham, Ralph S. Baric, Fang Li
The recent emergence of Wuhan coronavirus (2019-nCoV) puts the world on alert. 2019-nCoV is reminiscent of the SARS-CoV outbreak in 2002 to 2003. Our decade-long structural studies on the receptor recognition by SARS-Co…
How to plan and perform a qualitative study using content analysis
4679 citations2016NursingPlus Open
Mariette Bengtsson
This paper describes the research process – from planning to presentation, with the emphasis on credibility throughout the whole process – when the methodology of qualitative content analysis is chosen in a qualitative…
AN INTEGRATIVE THEORY OF LOCUS COERULEUS-NOREPINEPHRINE FUNCTION: Adaptive Gain and Optimal Performance
4679 citations2005Annual Review of Neuroscience
Gary Aston‐Jones, Jonathan D. Cohen
Historically, the locus coeruleus-norepinephrine (LC-NE) system has been implicated in arousal, but recent findings suggest that this system plays a more complex and specific role in the control of behavior than investi…
Six views of embodied cognition
4679 citations2002Psychonomic Bulletin & Review
Margaret Wilson
circlize implements and enhances circular visualization in R
4678 citations2014Bioinformatics
Zuguang Gu, Lei Gu, Roland Eils, Matthias Schlesner, Benedikt Brors
SUMMARY: Circular layout is an efficient way for the visualization of huge amounts of genomic information. Here we present the circlize package, which provides an implementation of circular layout generation in R as wel…
GhostNet: More Features From Cheap Operations
4677 citations2020Unknown source
Kai Han, Yunhe Wang, Qi Tian, Jianyuan Guo, Chunjing Xu
Deploying convolutional neural networks (CNNs) on embedded devices is difficult due to the limited memory and computation resources. The redundancy in feature maps is an important characteristic of those successful CNNs…
Alliances and networks
4677 citations1998Strategic Management Journal
Ranjay Gulati
This paper introduces a social network perspective to the study of strategic alliances. It extends prior research, which has primarily considered alliances as dyadic exchanges and paid less attention to the fact that ke…
On Pixel-Wise Explanations for Non-Linear Classifier Decisions by Layer-Wise Relevance Propagation
4676 citations2015PLoS ONE
Sebastian Bach, Alexander Binder, Grégoire Montavon, Frederick Klauschen, Klaus‐Robert Müller
Understanding and interpreting classification decisions of automated image classification systems is of high value in many applications, as it allows to verify the reasoning of the system and provides additional informa…
Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease
4676 citations1997JAMA
Lindsay A. Farrer
OBJECTIVE: To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations. DATA SOURCES: Forty resear…
Survey of multi-objective optimization methods for engineering
4675 citations2004Structural and Multidisciplinary Optimization
R. Timothy Marler, Jasbir S. Arora
Phylogenies and Community Ecology
4675 citations2002Annual Review of Ecology and Systematics
Campbell O. Webb, David D. Ackerly, Mark A. McPeek, Michael J. Donoghue
▪ Abstract As better phylogenetic hypotheses become available for many groups of organisms, studies in community ecology can be informed by knowledge of the evolutionary relationships among coexisting species. We note t…
An Improved In Situ and Satellite SST Analysis for Climate
4675 citations2002Journal of Climate
Richard W. Reynolds, Nick A Rayner, Thomas M. Smith, Diane Stokes, Wanqiu Wang
A weekly 1° spatial resolution optimum interpolation (OI) sea surface temperature (SST) analysis has been produced at the National Oceanic and Atmospheric Administration (NOAA) using both in situ and satellite data from…
The Hopkins Symptom Checklist (HSCL): A self-report symptom inventory
4674 citations1974Systems Research and Behavioral Science
Leonard R. Derogatis, Ronald S. Lipman, Karl Rickels, E. H. Uhlenhuth, Lino Covi
This report describes the historical evolution, development, rationale and validation of the Hopkins Symptom Checklist (HSCL), a self-report symptom inventory. The HSCL is comprised of 58 items which are representative…
Metagenomic Analysis of the Human Distal Gut Microbiome
4673 citations2006Science
Steven R. Gill, Mihai Pop, Robert T. DeBoy, Paul B. Eckburg, Peter J. Turnbaugh
The human intestinal microbiota is composed of 10(13) to 10(14) microorganisms whose collective genome ("microbiome") contains at least 100 times as many genes as our own genome. We analyzed approximately 78 million bas…
Glossary of transcript symbols with an introduction
4673 citations2004Pragmatics & beyond. New series
Gail Jefferson
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism
4673 citations1961Nature
Peter Mitchell
RAxML-NG: a fast, scalable and user-friendly tool for maximum likelihood phylogenetic inference
4672 citations2019Bioinformatics
Alexey M. Kozlov, Diego Darriba, Tomáš Flouri, Benoît Morel, Alexandros Stamatakis
MOTIVATION: Phylogenies are important for fundamental biological research, but also have numerous applications in biotechnology, agriculture and medicine. Finding the optimal tree under the popular maximum likelihood (M…
Inflammation and insulin resistance
4672 citations2006Journal of Clinical Investigation
Steven E. Shoelson
Over a hundred years ago, high doses of salicylates were shown to lower glucose levels in diabetic patients. This should have been an important clue to link inflammation to the pathogenesis of type 2 diabetes (T2D), but…
Stochastic differential equations and applications
4671 citations2008Woodhead Publishing Limited eBooks
Xuerong Mao
This advanced undergraduate and graduate text has now been revised and updated to cover the basic principles and applications of various types of stochastic systems, with much on theory and applications not previously a…
Tectonic discrimination of granitoids
4671 citations1989Geological Society of America Bulletin
P.D. Maniar, Philip M. Piccoli
Research Article| May 01, 1989 Tectonic discrimination of granitoids PAPU D. MANIAR; PAPU D. MANIAR 1Department of Geology and Planetary Science, University of Pittsburgh, Pittsburgh, Pennsylvania 15260 Search for other…
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
4670 citations1991Nature
Alison Goate, Marie‐Christine Chartier‐Harlin, Mike Mullan, Jeremy Brown, Fiona Crawford
The Rules of Sociological Method
4670 citations1982Unknown source
Émile Durkheim
This series aims to create a forum for debate between different theoretical and philosophical traditions in the social sciences. As well as covering broad schools of thought, the series will also concentrate upon the wo…
Scalable Person Re-identification: A Benchmark
4669 citations2015Unknown source
Liang Zheng, Liyue Shen, Lu Tian, Shengjin Wang, Jingdong Wang
This paper contributes a new high quality dataset for person re-identification, named "Market-1501". Generally, current datasets: 1) are limited in scale, 2) consist of hand-drawn bboxes, which are unavailable under rea…
Central sensitization: Implications for the diagnosis and treatment of pain
4668 citations2010Pain
Clifford J. Woolf
Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central sensitization. Central sensitization mani…
Methods for integrating moderation and mediation: A general analytical framework using moderated path analysis.
4668 citations2007Psychological Methods
Jeffrey R. Edwards, Lisa Schurer Lambert
Studies that combine moderation and mediation are prevalent in basic and applied psychology research. Typically, these studies are framed in terms of moderated mediation or mediated moderation, both of which involve sim…
Replica-exchange molecular dynamics method for protein folding
4668 citations1999Chemical Physics Letters
Yuji Sugita, Yuko Okamoto
Applied Linear Regression Models
4668 citations1997Technometrics
Part1 Simple Linear Regression 1Linear Regression with One Predictor Variable 2Inferences in Regression and Correlation Analysis 3Diagnostics and Remedial Measures 4 Simultaneous Inferences and Other Topics in Regressio…
Suppression of acoustic noise in speech using spectral subtraction
4668 citations1979IEEE Transactions on Acoustics Speech and Signal Processing
S. Boll
A stand-alone noise suppression algorithm is presented for reducing the spectral effects of acoustically added noise in speech. Effective performance of digital speech processors operating in practical environments may…
Applied Longitudinal Analysis
4667 citations2011Wiley series in probability and statistics
Garrett M. Fitzmaurice, Nan M. Laird, James H. Ware
Praise for the First Edition ". . . [this book] should be on the shelf of everyone interested in . . . longitudinal data analysis."-Journal of the American Statistical Association Features newly developed topics and app…
The Sickness Impact Profile: Development and Final Revision of a Health Status Measure
4667 citations1981Medical Care
Marilyn Bergner, Ruth A. Bobbitt, William B. Carter, Betty S. Gilson
The final development of the Sickness Impact Profile (SIP), a behaviorally based measure of health status, is presented. A large field trial on a random sample of prepaid group practice enrollees and smaller trials on s…
Statistical thermodynamics of liquid mixtures: A new expression for the excess Gibbs energy of partly or completely miscible systems
4667 citations1975AIChE Journal
D. S. Abrams, John M. Prausnitz
Abstract To obtain a semi‐theoretical equation for the excess Gibbs energy of a liquid mixture, Guggenheim's quasi‐chemical analysis is generalized through introduction of the local area fraction as the primary concentr…
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
4666 citations1999Nature Biotechnology
Steven P. Gygi, Beate Rist, Scott A. Gerber, František Tureček, Michael H. Gelb
The Aggression Questionnaire.
4666 citations1992Journal of Personality and Social Psychology
Arnold H. Buss, Mark Perry
From transactional to transformational leadership: Learning to share the vision
4665 citations1990Organizational Dynamics
Bernard M. Bass
Making sense of implementation theories, models and frameworks
4664 citations2015Implementation Science
Per Nilsén
BACKGROUND: Implementation science has progressed towards increased use of theoretical approaches to provide better understanding and explanation of how and why implementation succeeds or fails. The aim of this article…
Activists beyond Borders
4664 citations2014Cornell University Press eBooks
Margaret E. Keck, Kathryn Sikkink
In Activists beyond Borders , Margaret E. Keck and Kathryn Sikkink examine a type of pressure group that has been largely ignored by political analysts: networks of activists that coalesce and operate across national fr…
Resilience Thinking: Integrating Resilience, Adaptability and Transformability
4664 citations2010Ecology and Society
Carl Folke, Stephen R. Carpenter, Brian Walker, Marten Scheffer, Terry Chapin
Folke, C., S. R. Carpenter, B. Walker, M. Scheffer, T. Chapin, and J. Rockström. 2010. Resilience thinking: integrating resilience, adaptability and transformability. Ecology and Society 15(4): 20. https://doi.org/10.57…
Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
4663 citations2018Hepatology
Jorge A. Marrero, Laura Kulik, Claude B. Sirlin, Andrew X. Zhu, Richard S. Finn
Marrero, Jorge A.; Kulik, Laura M.; Sirlin, Claude B.; Zhu, Andrew X.; Finn, Richard S.; Abecassis, Michael M.; Roberts, Lewis R.; Heimbach, Julie K. Author Information
Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects
4663 citations2007New England Journal of Medicine
Lars Sjöström, Kristina Narbro, C. David Sjöström, Kristjan Karason, Bo Larsson
BACKGROUND: Obesity is associated with increased mortality. Weight loss improves cardiovascular risk factors, but no prospective interventional studies have reported whether weight loss decreases overall mortality. In f…
Rank-Order Tournaments as Optimum Labor Contracts
4663 citations1981Journal of Political Economy
Edward P. Lazear, Sherwin Rosen
This paper analyzes compensation schemes which pay according to an individual's ordinal rank in an organization rather than his output level. When workers are risk neutral, it is shown that wages based upon rank induce…
Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ
4663 citations1977Science
W. David Benton, Ronald W. Davis
A rapid, direct method for screening single plaques of Agt recombinant phage is described. The method allows at least 10(6) clones to be screened per day and simplifies physical containment of recombinants.
Sox9 Modulates Proliferation and Expression of Osteogenic Markers of Adipose-Derived Stem Cells (ASC)
4662 citations2013Cellular Physiology and Biochemistry
Sabine Stöckl, Claudia Göttl, Joachim Grifka, Susanne Grässel
BACKGROUND: Mesenchymal stem cells (MSC) are promising tools for tissue-engineering and musculoskeletal regeneration. They reside within various tissues, like adipose tissue, periosteum, synovia, muscle, dermis, blood a…
Attention Deficit Hyperactivity Disorder: A Handbook for Diagnosis and Treatment
4662 citations1994Behavioral Disorders
Russell A. Barkley, Mary Jo Poillion
The purpose [of this book] is to present as much practical information as possible, rather than to give an exhaustive or critical review of the research literature. Coverage includes differential diagnosis, a developmen…
The entity-relationship model—toward a unified view of data
4662 citations1976ACM Transactions on Database Systems
Peter Pin-Shan Chen
A data model, called the entity-relationship model, is proposed. This model incorporates some of the important semantic information about the real world. A special diagrammatic technique is introduced as a tool for data…
Bias reduction of maximum likelihood estimates
4661 citations1993Biometrika
David Firth
It is shown how, in regular parametric problems, the first-order term is removed from the asymptotic bias of maximum likelihood estimates by a suitable modification of the score function. In exponential families with ca…
Alone together: why we expect more from technology and less from each other
4660 citations2011Choice Reviews Online
Fernández Pedemonte, Damián
Turkle, Sherry.Alone together: why we expect more from technology and less from each other?New York: Basic Books,
Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations.
4660 citations1991Proceedings of the National Academy of Sciences
Richard W. Michelmore, Ilan Paran, Rick Kesseli
We developed bulked segregant analysis as a method for rapidly identifying markers linked to any specific gene or genomic region. Two bulked DNA samples are generated from a segregating population from a single cross. E…
A new force field for molecular mechanical simulation of nucleic acids and proteins
4659 citations1984Journal of the American Chemical Society
Scott J. Weiner, Peter A. Kollman, David A. Case, U. Chandra Singh, Caterina Ghio
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA new force field for molecular mechanical simulation of nucleic acids and proteinsScott J. Weiner, Peter A. Kollman, David A. Case, U. Chandra Singh, Caterina Ghio, Guliano A…
Molecular and cellular insights into T cell exhaustion
4658 citations2015Nature reviews. Immunology
E. John Wherry, Makoto Kurachi
Data mining and knowledge discovery: making sense out of data
4658 citations1996IEEE Expert
U.M. Feyyad
Current computing and storage technology is rapidly outstripping society's ability to make meaningful use of the torrent of available data. Without a concerted effort to develop knowledge discovery techniques, organizat…
Second Language Acquisition and Second Language Learning
4658 citations1989Modern Language Journal
Elizabeth B. Bernhardt, Stephen Krashen
Surface Studies by Scanning Tunneling Microscopy
4658 citations1982Physical Review Letters
G. Binnig, H. Rohrer, Ch. Gerber, E. Weibel
Surface microscopy using vacuum tunneling is demonstrated for the first time. Topographic pictures of surfaces on an atomic scale have been obtained. Examples of resolved monoatomic steps and surface reconstructions are…
The Limiting Similarity, Convergence, and Divergence of Coexisting Species
4658 citations1967The American Naturalist
Robert H. MacArthur, Richard Levins
1. There is a limit to the similarity (and hence to the number) of competing species which can coexist. The total number of species is proportional to the total range of the environment divided by the niche breadth of t…
Ecological Linkages Between Aboveground and Belowground Biota
4657 citations2004Science
David A. Wardle, Richard D. Bardgett, John N. Klironomos, Heikki Setälä, Wim H. van der Putten
All terrestrial ecosystems consist of aboveground and belowground components that interact to influence community- and ecosystem-level processes and properties. Here we show how these components are closely interlinked…
Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3
4657 citations2003The Journal of Experimental Medicine
WanJun Chen, Wenwen Jin, Neil J. Hardegen, Ke-Jian Lei, Li Li
CD4+CD25+ regulatory T cells (Treg) are instrumental in the maintenance of immunological tolerance. One critical question is whether Treg can only be generated in the thymus or can differentiate from peripheral CD4+CD25…
Evaluating the use of “goodness‐of‐fit” Measures in hydrologic and hydroclimatic model validation
4657 citations1999Water Resources Research
David R. Legates, Gregory J. McCabe
Correlation and correlation‐based measures (e.g., the coefficient of determination) have been widely used to evaluate the “goodness‐of‐fit” of hydrologic and hydroclimatic models. These measures are oversensitive to ext…
A Calculus of Communicating Systems
4655 citations1980Lecture notes in computer science
To saturate or not to saturate? Questioning data saturation as a useful concept for thematic analysis and sample-size rationales
4654 citations2019Qualitative Research in Sport Exercise and Health
Virginia Braun, Victoria Clarke
The concept of data saturation, defined as ‘information redundancy’ or the point at which no new themes or codes ‘emerge’ from data, is widely referenced in thematic analysis (TA) research in sport and exercise, and bey…
Cell Death
4654 citations2004Cell
Nika N. Danial, Stanley J. Korsmeyer
The future of distributed models: Model calibration and uncertainty prediction
4654 citations1992Hydrological Processes
K. Beven, Andrew Binley
Abstract This paper describes a methodology for calibration and uncertainty estimation of distributed models based on generalized likelihood measures. the GLUE procedure works with multiple sets of parameter values and…
Some Characteristics of Simple Types of Predation and Parasitism
4654 citations1959The Canadian Entomologist
C. S. Holling
In an earlier study (Holling, 1959) the basic and subsidiary components of predation were demonstrated in a predator-prey situation involving the predation of sawfly cocoons by small mammals. One of the basic components…
Increased Prevalence of Sleep-Disordered Breathing in Adults
4653 citations2013American Journal of Epidemiology
P. E. Peppard, Terry Young, Jodi H. Barnet, M. Palta, Erika W. Hagen
Sleep-disordered breathing is a common disorder with a range of harmful sequelae. Obesity is a strong causal factor for sleep-disordered breathing, and because of the ongoing obesity epidemic, previous estimates of slee…
Pattern Recognition and Machine Learning
4653 citations2007Technometrics
Radford M. Neal
(2007). Pattern Recognition and Machine Learning. Technometrics: Vol. 49, No. 3, pp. 366-366.
THE ROLE OF ROOT EXUDATES IN RHIZOSPHERE INTERACTIONS WITH PLANTS AND OTHER ORGANISMS
4653 citations2006Annual Review of Plant Biology
Harsh P. Bais, Tiffany L. Weir, Laura G. Perry, Simon Gilroy, Jorge M. Vivanco
The rhizosphere encompasses the millimeters of soil surrounding a plant root where complex biological and ecological processes occur. This review describes recent advances in elucidating the role of root exudates in int…
Synchronization
4653 citations2001Cambridge University Press eBooks
Arkady Pikovsky, Michael Rosenblum, Jürgen Kurths
First recognized in 1665 by Christiaan Huygens, synchronization phenomena are abundant in science, nature, engineering and social life. Systems as diverse as clocks, singing crickets, cardiac pacemakers, firing neurons…
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
4653 citations1997Science
Darwin J. Prockop
Marrow stromal cells can be isolated from other cells in marrow by their tendency to adhere to tissue culture plastic. The cells have many of the characteristics of stem cells for tissues that can roughly be defined as…
The trinity of COVID-19: immunity, inflammation and intervention
4652 citations2020Nature reviews. Immunology
Matthew Zirui Tay, Chek Meng Poh, Laurent Rénia, Paul A. MacAry, Lisa F. P. Ng
Nitrous Oxide (N 2 O): The Dominant Ozone-Depleting Substance Emitted in the 21st Century
4652 citations2009Science
A. R. Ravishankara, J. S. Daniel, R. W. Portmann
Unwelcome Dominance Stratospheric ozone is depleted by many different chemicals; most prominently, chlorofluorocarbons (CFCs) responsible for causing the Antarctic ozone hole. Nitrous oxide is also an ozone-depleting su…
Liberals and conservatives rely on different sets of moral foundations.
4652 citations2009Journal of Personality and Social Psychology
Jesse Graham, Jonathan Haidt, Brian A. Nosek
How and why do moral judgments vary across the political spectrum? To test moral foundations theory (J. Haidt & J. Graham, 2007; J. Haidt & C. Joseph, 2004), the authors developed several ways to measure people's use of…
Global analysis of nitrogen and phosphorus limitation of primary producers in freshwater, marine and terrestrial ecosystems
4652 citations2007Ecology Letters
James J. Elser, Matthew E. S. Bracken, Elsa E. Cleland, Daniel S. Gruner, W. Stanley Harpole
The cycles of the key nutrient elements nitrogen (N) and phosphorus (P) have been massively altered by anthropogenic activities. Thus, it is essential to understand how photosynthetic production across diverse ecosystem…
Justice, Nature and the Geography of Difference
4651 citations1997Geographical Review
Kent Mathewson, David Harvey
Thoughts for a Prologue. Introduction. Part I: Orientations. 1. Militant Particularism and Global Ambition. 2. Dialectics. 3. A Cautionary Tale on Internal Relations. 4. The Dialectics of Discourse. 5. Historical Agency…
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
4650 citations2000Nature
C. Kendall Stover, X. Q. Pham, Alice L. Erwin, Sentaro Mizoguchi, Paul Warrener
THE META-ANALYSIS OF RESPONSE RATIOS IN EXPERIMENTAL ECOLOGY
4650 citations1999Ecology
Larry V. Hedges, Jessica Gurevitch, Peter S. Curtis
Meta-analysis provides formal statistical techniques for summarizing the results of independent experiments and is increasingly being used in ecology. The response ratio (the ratio of mean outcome in the experimental gr…
Population growth makes waves in the distribution of pairwise genetic differences.
4650 citations1992Molecular Biology and Evolution
Alan R. Rogers, Henry Harpending
Episodes of population growth and decline leave characteristic signatures in the distribution of nucleotide (or restriction) site differences between pairs of individuals. These signatures appear in histograms showing t…
Seven Principles for Good Practice in Undergraduate Education
4650 citations1989Biochemical Education
Arthur W. Chickering, Zelda F. Gamson
Structure and Dynamics of the TIP3P, SPC, and SPC/E Water Models at 298 K
4649 citations2001The Journal of Physical Chemistry A
Pekka Mark, Lennart Nilsson
Molecular dynamics simulations of five water models, the TIP3P (original and modified), SPC (original and refined), and SPC/E (original), were performed using the CHARMM molecular mechanics program. All simulations were…
Using Technology and Constituting Structures: A Practice Lens for Studying Technology in Organizations
4649 citations2000Organization Science
Wanda J. Orlikowski
As both technologies and organizations undergo dramatic changes in form and function, organizational researchers are increasingly turning to concepts of innovation, emergence, and improvisation to help explain the new w…
Semantic Interpretation in Generative Grammar
4649 citations1975Language
Robert Freidin, Ray Jackendoff
Like other recent work in the field of generative-transformational grammar, this book developed from a realization that many problems in linguistics involve semantics too deeply to be solved insightfully within the synt…
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
4648 citations2018Nucleic Acids Research
Annalisa Buniello, Jacqueline A. L. MacArthur, María Cerezo, Laura W. Harris, James Hayhurst
The GWAS Catalog delivers a high-quality curated collection of all published genome-wide association studies enabling investigations to identify causal variants, understand disease mechanisms, and establish targets for…
How a century of ammonia synthesis changed the world
4648 citations2008Nature Geoscience
Jan Willem Erisman, Mark A. Sutton, James N. Galloway, Zbigniew Klimont, Wilfried Winiwarter
Method for Solving the Korteweg-deVries Equation
4648 citations1967Physical Review Letters
Clifford S. Gardner, J. M. Greene, Martin D. Kruskal, Robert M. Miura
A method for solving the initial-value problem of the Korteweg-deVries equation is presented which is applicable to initial data that approach a constant sufficiently rapidly as $|x|\ensuremath{\rightarrow}\ensuremath{\…
mRNA vaccines — a new era in vaccinology
4647 citations2018Nature Reviews Drug Discovery
Norbert Pardi, Michael J. Hogan, Frederick Porter, Drew Weissman
Exchange bias
4646 citations1999Journal of Magnetism and Magnetic Materials
J. Nogués, Iván K. Schuller
A global model of natural volatile organic compound emissions
4646 citations1995Journal of Geophysical Research Atmospheres
Alex Guenther, C. N. Hewitt, David J. Erickson, Ray Fall, Chris Geron
Numerical assessments of global air quality and potential changes in atmospheric chemical constituents require estimates of the surface fluxes of a variety of trace gas species. We have developed a global model to estim…
Organization and Expression of Eucaryotic Split Genes Coding for Proteins
4646 citations1981Annual Review of Biochemistry
Richard Breathnach, Pierre Chambon
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell gro…
Rechargeable Lithium–Sulfur Batteries
4645 citations2014Chemical Reviews
Arumugam Manthiram, Yongzhu Fu, Sheng‐Heng Chung, Chenxi Zu, Yu‐Sheng Su
ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTRechargeable Lithium–Sulfur BatteriesArumugam Manthiram*, Yongzhu Fu, Sheng-Heng Chung, Chenxi Zu, and Yu-Sheng SuView Author Information Materials Science and Engineering Prog…
The Revision of ISO Standards 14040-3 - ISO 14040: Environmental management Life cycle assessment Principles and framework - ISO 14044: Environmental management Life cycle assessment Requirements and guidelines
4645 citations2005The International Journal of Life Cycle Assessment
Hans-Jürgen Klüppel
Quantum theory, the Church–Turing principle and the universal quantum computer
4645 citations1985Proceedings of the Royal Society of London A Mathematical and Physical Sciences
David Deutsch
Abstract It is argued that underlying the Church–Turing hypothesis there is an implicit physical assertion. Here, this assertion is presented explicitly as a physical principle: ‘every finitely realizible physical syste…
Reference Crop Evapotranspiration from Temperature
4645 citations1985Applied Engineering in Agriculture
George H. Hargreaves, Zohrab Samani
MEASURED lysimeter evapotranspiration of Alta fescue grass (a cool season grass) is taken as an index of reference crop evapotranspiration (ETo). An equation is presented that estimates ETo from measured values of daily…
Unequal childhoods: class, race, and family life
4644 citations2004Choice Reviews Online
Annette Lareau
Class does make a difference in the lives and futures of American children. Drawing on in-depth observations of black and white middle-class, working-class, and poor families, Unequal childhoods explores this fact, offe…
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
4644 citations1992Nature
Dorit Shweiki, Ahuva Itin, Dov Soffer, Eli Keshet
Lead Users: A Source of Novel Product Concepts
4644 citations1986Management Science
Eric von Hippel
Accurate marketing research depends on accurate user judgments regarding their needs. However, for very novel products or in product categories characterized by rapid change—such as “high technology” products—most poten…
Chlorophyll Fluorescence: A Probe of Photosynthesis In Vivo
4643 citations2008Annual Review of Plant Biology
Neil R. Baker
The use of chlorophyll fluorescence to monitor photosynthetic performance in algae and plants is now widespread. This review examines how fluorescence parameters can be used to evaluate changes in photosystem II (PSII)…
DNA Repair and Mutagenesis
4643 citations2005ASM Press eBooks
Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz
DNA damage Mutations The reversal of base damage Base excision repair Nucleotide excision repair in prokaryotes Nucleotide excision repair in lower eukaryotes Nucleotide excision repair in mammalian cells: general consi…
National Kidney Foundation Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification
4643 citations2003Annals of Internal Medicine
Andrew S. Levey, Josef Coresh, Ethan M. Balk, Annamaria T. Kausz, Adeera Levin
Chronic kidney disease is a worldwide public health problem with an increasing incidence and prevalence, poor outcomes, and high cost. Outcomes of chronic kidney disease include not only kidney failure but also complica…