Programmatic discovery

Top cited papers, continuously indexable.

This page pulls one slice of the highest-cited DOI-backed works from OpenAlex and links every result to its branded resea.org DOI page. It exists to create crawl paths, not just a single vanity landing.

Neoantigens in cancer immunotherapy

4831 citations2015Science
Ton N. Schumacher, Robert D. Schreiber

The clinical relevance of T cells in the control of a diverse set of human cancers is now beyond doubt. However, the nature of the antigens that allow the immune system to distinguish cancer cells from noncancer cells h…

Modernity and Self-Identity

4828 citations2023Unknown source
Anthony Giddens

A person with a reasonably stable sense of self-identity has a feeling of biographical continuity which she is able to grasp reflexively and, to a greater or lesser degree, communicate to other people. In conditions of…

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

4827 citations2024The Lancet
Alize J Ferrari, Damian Santomauro, Amirali Aali, Yohannes Abate, Cristiana Abbafati

BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury…

Physical Properties of Carbon Nanotubes

4827 citations1998IMPERIAL COLLEGE PRESS eBooks
R. Saito, G. Dresselhaus, M. S. Dresselhaus

This is an introductory textbook for graduate students and researchers from various fields of science who wish to learn about carbon nanotubes. The field is still at an early stage, and progress continues at a rapid rat…

ON THE CONSTRUCTION OF A SOCIAL REALITY

4826 citations2018University of Iowa Press eBooks
John R. 1932-2025 Searle

This short treatise looks at how we construct a social reality from our sense impressions; at how, for example, we construct a five-pound note with all that implies in terms of value and social meaning, from the printed…

Skyrmion Lattice in a Chiral Magnet

4826 citations2009Science
S. Mühlbauer, B. Binz, Florian Jonietz, C. Pfleiderer, Achim Rosch

Skyrmions represent topologically stable field configurations with particle-like properties. We used neutron scattering to observe the spontaneous formation of a two-dimensional lattice of skyrmion lines, a type of magn…

Whence Consumer Loyalty?

4822 citations1999Journal of Marketing
Richard L. Oliver

Both practitioners and academics understand that consumer loyalty and satisfaction are linked inextricably. They also understand that this relation is asymmetric. Although loyal consumers are most typically satisfied, s…

ON THE VALIDATION OF MODELS

4820 citations1981Physical Geography
Cort J. Willmott

Traditional methods of evaluating geographic models by statistical comparisons between observed and simulated variates are criticized. In particular, it is suggested that the correlation coefficient (r), its square and…

The Next Generation of the Penn World Table

4817 citations2015American Economic Review
Robert C. Feenstra, Robert Inklaar, Marcel P. Timmer

We describe the theory and practice of real GDP comparisons across countries and over time. Version 8 of the Penn World Table expands on previous versions in three respects. First, in addition to comparisons of living s…

Lost in knowledge translation: Time for a map?

4815 citations2006Journal of Continuing Education in the Health Professions
Ian D. Graham, Jo Logan, Margaret B. Harrison, Sharon E. Straus, Jacqueline Tetroe

There is confusion and misunderstanding about the concepts of knowledge translation, knowledge transfer, knowledge exchange, research utilization, implementation, diffusion, and dissemination. We review the terms and de…

An introduction to hidden Markov models

4811 citations1986IEEE ASSP Magazine
L. R. Rabiner, Biing‐Hwang Juang

The basic theory of Markov chains has been known to mathematicians and engineers for close to 80 years, but it is only in the past decade that it has been applied explicitly to problems in speech processing. One of the…

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ 1 and χ 2 Dihedral Angles

4810 citations2012Journal of Chemical Theory and Computation
Robert B. Best, Xiao Zhu, Jihyun Shim, Pedro E. M. Lopes, Jeetain Mittal

While the quality of the current CHARMM22/CMAP additive force field for proteins has been demonstrated in a large number of applications, limitations in the model with respect to the equilibrium between the sampling of…

Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization

4810 citations1998Molecular Biology of the Cell
Paul T. Spellman, Gavin Sherlock, Michael Q. Zhang, Vishwanath R. Iyer, Kirk R. Anders

We sought to create a comprehensive catalog of yeast genes whose transcript levels vary periodically within the cell cycle. To this end, we used DNA microarrays and samples from yeast cultures synchronized by three inde…