Top cited papers, continuously indexable.

This review covers computer-assisted analysis of images in the field of medical imaging. Recent advances in machine learning, especially with regard to deep learning, are helping to identify, classify, and quantify patt…

Metastasis causes most cancer deaths, yet this process remains one of the most enigmatic aspects of the disease. Building on new mechanistic insights emerging from recent research, we offer our perspective on the metast…

The appearance of active galactic nuclei (AGN) depends so strongly on orientation that our current classification schemes are dominated by random pointing directions instead of more interesting physical properties. Ligh…

In an attempt to explain how and why some individuals with musculoskeletal pain develop a chronic pain syndrome, Lethem et al. (Lethem J, Slade PD, Troup JDG, Bentley G. Outline of fear-avoidance model of exaggerated pa…

The Tractatus Logico-Philosophicus first appeared in 1921 and was the only philosophical work that Ludwig Wittgenstein (1889-1951) published during his lifetime. Written in short, carefully numbered paragraphs of extrem…

The brain is the key organ of the response to stress because it determines what is threatening and, therefore, potentially stressful, as well as the physiological and behavioral responses which can be either adaptive or…

Huntington's thesis is the repetitive trying to masquerade as the original or the profound! This book is actually an expan sion of a 27-page article on the Clash of Civilisations pub lished by Huntingdon in Foreign Affa…

BACKGROUND: We aimed to assess the safety and efficacy of thrombectomy for the treatment of stroke in a trial embedded within a population-based stroke reperfusion registry. METHODS: During a 2-year period at four cente…

Similar to its popular older cousins the fullerene, the carbon nanotube, and graphene, the latest form of nanocarbon, the carbon nanodot, is inspiring intensive research efforts in its own right. These surface-passivate…

Demonstrates how the chemical structure of organic compounds influences\nthe molecular interactions which control transfer and reaction processes in\nthe natural environment. Thoroughly explains how to quantify these pr…

We develop a model to explain how images of one's work organization shape the strength of his or her identification with the organization. We focus on two key organizational images: one based on what a member believes i…

Abstract—We describe the design of Kaldi, a free, open-source toolkit for speech recognition research. Kaldi provides a speech recognition system based on finite-state transducers (using the freely available OpenFst), t…

In 1995, the International Association for the Properties of Water and Steam (IAPWS) adopted a new formulation called “The IAPWS Formulation 1995 for the Thermodynamic Properties of Ordinary Water Substance for General…

Bulk metallic glasses (BMGs) have been classified according to the atomic size difference, heat of mixing (ΔHmix) and period of the constituent elements in the periodic table. The BMGs discovered to date are classified…

Policy-makers are considering large-scale programs aimed at self-control to improve citizens' health and wealth and reduce crime. Experimental and economic studies suggest such programs could reap benefits. Yet, is self…

Latent Semantic Analysis (LSA) is a theory and method for extracting and representing the contextual‐usage meaning of words by statistical computations applied to a large corpus of text (Landauer & Dumais, 1997). The un…

Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper induces cell death, howev…

A method is developed for representing any communication system geometrically. Messages and the corresponding signals are points in two function spaces, and the modulation process is a mapping of one space into the othe…

This paper studies the asymptotic properties of instrumental variable (IV) estimates of multivariate cointegrating regressions and allows for deterministic and stochastic regressors as well as quite general deterministi…

Rapid progress has been made in the understanding of the molecular interactions that result in cell adhesion. Many adhesive proteins present in extracellular matrices and in the blood contain the tripeptide arginine-gly…

The violence wrought by climate change, toxic drift, deforestation, oil spills, and the environmental aftermath of war takes place gradually and often invisibly. Using the innovative concept of “slow violence” to descri…

We describe an open-source toolkit for statistical machine translation whose novel contributions are (a) support for linguistically motivated factors, (b) confusion network decoding, and (c) efficient data formats for t…

Abstract Reactive oxygen species (ROS) are key signaling molecules that play an important role in the progression of inflammatory disorders. An enhanced ROS generation by polymorphonuclear neutrophils (PMNs) at the site…

We introduce complexity parameters for time series based on comparison of neighboring values. The definition directly applies to arbitrary real-world data. For some well-known chaotic dynamical systems it is shown that…

BACKGROUND: Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle interventi…

Organismal life encounters reactive oxidants from internal metabolism and environmental toxicant exposure. Reactive oxygen and nitrogen species cause oxidative stress and are traditionally viewed as being harmful. On th…

This review covers the literature published in 2008 for marine natural products, with 829 citations (613 for the period January to December 2008) referring to compounds isolated from marine microorganisms and phytoplank…

Distilling the vast literature on this frequently studied variable in organizational behaviour research, Paul E Spector provides the student and professional with a pithy overview of the application, assessment, causes…

Les auteurs cherchent a savoir si l'humeur dans lequel le sujet se trouve au moment ou on lui demande d'evaluer sa satisfaction existentielle, influence precisement ces evaluations

International audience

Molecular mechanics Poisson-Boltzmann surface area (MM-PBSA), a method to estimate interaction free energies, has been increasingly used in the study of biomolecular interactions. Recently, this method has also been app…

Graphene's success has shown that it is possible to create stable, single and few-atom-thick layers of van der Waals materials, and also that these materials can exhibit fascinating and technologically useful properties…

List of Figures Preface 1. Orientations 1: The Problem, the Setting, and the Approach 2. Orientations 2: Culture, Health Care Systems, and Clinical Reality 3. Orientations 3: Core Clinical Functions and Explanatory Mode…

In this, his most famous work, Marcel Mauss presented to the world a book which revolutionized our understanding of some of the basic structures of society. By identifying the complex web of exchange and obligation invo…

DNA-DNA hybridization (DDH) values have been used by bacterial taxonomists since the 1960s to determine relatedness between strains and are still the most important criterion in the delineation of bacterial species. Sin…

This article describes a procedure for the study of destructive obedience in the laboratory. It consists of ordering a naive S to administer increasingly more severe punishment to a victim in the context of a learning e…

Organic aerosol (OA) particles affect climate forcing and human health, but their sources and evolution remain poorly characterized. We present a unifying model framework describing the atmospheric evolution of OA that…

We propose that the crucial difference between human cognition and that of other species is the ability to participate with others in collaborative activities with shared goals and intentions: shared intentionality. Par…

Abstract Since the 1980s the rise of so-called ‘populist parties’ has given rise to thousands of books, articles, columns and editorials. This article aims to make a threefold contribution to the current debate on popul…

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdsorption and surface-enhanced Raman of dyes on silver and gold solsP. C. Lee and D. MeiselCite this: J. Phys. Chem. 1982, 86, 17, 3391–3395Publication Date (Print):August 1,…

Immune checkpoint therapy, which targets regulatory pathways in T cells to enhance antitumor immune responses, has led to important clinical advances and provided a new weapon against cancer. This therapy has elicited d…

This article concerns the nature of evoked brain responses and the principles underlying their generation. We start with the premise that the sensory brain has evolved to represent or infer the causes of changes in its…

A new measure of strange attractors is introduced which offers a practical algorithm to determine their character from the time series of a single observable. The relation of this new measure to fractal dimension and in…

The Ribosomal Database Project (RDP) provides researchers with quality-controlled bacterial and archaeal small subunit rRNA alignments and analysis tools. An improved alignment strategy uses the Infernal secondary struc…

The author discusses 3 variables that assess different aspects of social relationships-social support, social integration, and negative interaction. The author argues that all 3 are associated with health outcomes, that…

Spatial pyramid pooling module or encode-decoder structure are used in deep neural networks for semantic segmentation task. The former networks are able to encode multi-scale contextual information by probing the incomi…

A revised and updated classification for the families of flowering plants is provided. Many recent studies have yielded increasingly detailed evidence for the positions of formerly unplaced families, resulting in a numb…

Although convolutional neural networks (CNNs) have achieved great success in computer vision, this work investigates a simpler, convolution-free backbone network use-fid for many dense prediction tasks. Unlike the recen…

We investigated the intracellular uptake of different sized and shaped colloidal gold nanoparticles. We showed that kinetics and saturation concentrations are highly dependent upon the physical dimensions of the nanopar…

(1990). Free Radicals in Biology and Medicine. International Journal of Radiation Biology: Vol. 58, No. 4, pp. 725-725.

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell gro…

Regional dropout strategies have been proposed to enhance performance of convolutional neural network classifiers. They have proved to be effective for guiding the model to attend on less discriminative parts of objects…

This is a revised version of the KatzNewcomb lecture presented at the University of Michigan, April 23-24, 1993. The 1993 lecture celebrated the life of Rensis Likert, the founding director of the Institute for Social R…

Contents: Introduction. The Problem and the Line of Attack. Summation and Learning in Perception. Field Theory and Equipotentiality. The First Stage of Perception: Growth of the Assembly. Perception of a Complex: The Ph…

We studied a large sample of male children from birth to adulthood to determine why some children who are maltreated grow up to develop antisocial behavior, whereas others do not. A functional polymorphism in the gene e…

The Extensible Markup Language XML is a fundamental data format for the World Wide Web which is widely in use. It is recommended by the World Wide Web Consortium (W3C) for data exchange and electronic publishing. In thi…

Zichao Yang, Diyi Yang, Chris Dyer, Xiaodong He, Alex Smola, Eduard Hovy. Proceedings of the 2016 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies. 2…

Organic thin-film transistors (OTFTs) have lived to see great improvements in recent years. This review presents new insight into conduction mechanisms and performance characteristics, as well as opportunities for model…

Human embryonic kidney cells have been transformed by exposing cells to sheared fragments of adenovirus type 5 DNA. The transformed cells (designated 293 cells) exhibited many of the characteristics of transformation in…

BACKGROUND: The purpose was to: 1) perform a systematic review of studies examining the relation between physical activity, fitness, and health in school-aged children and youth, and 2) make recommendations based on the…

This chapter contains sections titled: Phenomenological aspects One-dimensional constitutive model General elastoplastic constitutive model Classical yield criteria Plastic flow rules Hardening laws

Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel met to develop guidelines for the use of the single-cell gel (SCG)/Comet assay in genetic t…

The interaction between spin waves and itinerant electrons is considerably enhanced in the vicinity of an interface between normal and ferromagnetic layers in metallic thin films. This leads to a local increase of the G…

The miRBase database aims to provide integrated interfaces to comprehensive microRNA sequence data, annotation and predicted gene targets. miRBase takes over functionality from the microRNA Registry and fulfils three ma…

This study describes possible transmission of novel coronavirus disease 2019 (COVID-19) from an asymptomatic Wuhan resident to 5 family members in Anyang, a Chinese city in the neighboring province of Hubei.

Traditionally, consumers used the Internet to simply expend content: they read it, they watched it, and they used it to buy products and services. Increasingly, however, consumers are utilizing platforms-such as content…

We present full sky microwave maps in five frequency bands (23 to 94 GHz) from the WMAP first year sky survey. Calibration errors are less than 0.5% and the low systematic error level is well specified. The cosmic micro…