Top cited papers, continuously indexable.

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Every 3 years, the American Cancer Society provides an update of CRC occurrence based on incidence data (available through 20…

BACKGROUND: Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck after platinum chemotherapy have a very poor prognosis and limited therapeutic options. Nivolumab, an anti-programmed death…

Nurse researchers typically provide evidence of content validity for instruments by computing a content validity index (CVI), based on experts' ratings of item relevance. We compared the CVI to alternative indexes and c…

After infection and a prolonged incubation period, the scrapie agent causes a degenerative disease of the central nervous system in sheep and goats. Six lines of evidence including sensitivity to proteases demonstrate t…

Possibly one of the most significant, yet most overlooked, works of the twentieth century, it was The Order of Things that established Foucault's reputation as an intellectual giant

"An Essay concerning Human Understanding" published on by null.

A simple theory is developed that accounts for many of the observed physical properties of micelles, both globular and rod-like, and of bilayer vesicles composed of ionic or zwitterionic amphiphiles. The main point of d…

"Options, Futures, and other Derivatives" an often suggested and recommended book by Professor John C. Hull, has over the years emerged the most preferred textbooks, especially in business management community and frate…

Problems involving causal inference have dogged at the heels of statistics since its earliest days. Correlation does not imply causation, and yet causal conclusions drawn from a carefully designed experiment are often v…

Adaptation has been defined and recognized by two different criteria: historical genesis (features built by natural selection for their present role) and current utility (features now enhancing fitness no matter how the…

We are given a large database of customer transactions, where each transaction consists of customer-id, transaction time, and the items bought in the transaction. We introduce the problem of mining sequential patterns o…

From the Publisher: In this age of DNA computers and artificial intelligence, information is becoming disembodied even as the bodies that once carried it vanish into virtuality. While some marvel at these changes, envis…

Top-down visual attention mechanisms have been used extensively in image captioning and visual question answering (VQA) to enable deeper image understanding through fine-grained analysis and even multiple steps of reaso…

Two types of nonlinear control algorithms are presented for uncertain linear plants. Controllers of the first type are stabilizing polynomial feedbacks that allow to adjust a guaranteed convergence time of system trajec…

We present cosmological parameter constraints based on the final nine-year Wilkinson Microwave Anisotropy Probe ( WMAP ) data, in conjunction with a number of additional cosmological data sets. The WMAP data alone, and…

Internet of Things (IoT) has provided a promising opportunity to build powerful industrial systems and applications by leveraging the growing ubiquity of radio-frequency identification (RFID), and wireless, mobile, and…

This article reviews a diverse set of proposals for dual processing in higher cognition within largely disconnected literatures in cognitive and social psychology. All these theories have in common the distinction betwe…

BACKGROUND: The PedsQL (Pediatric Quality of Life Inventory) (Children's Hospital and Health Center, San Diego, California) is a modular instrument for measuring health-related quality of life (HRQOL) in children and ad…

BACKGROUND: An integrative theoretical framework, developed for cross-disciplinary implementation and other behaviour change research, has been applied across a wide range of clinical situations. This study tests the va…

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Humans and animals learn much better when the examples are not randomly presented but organized in a meaningful order which illustrates gradually more concepts, and gradually more complex ones. Here, we formalize such t…

Numerous modifications to the Kain-Fritsch convective parameterization have been implemented over the last decade. These modifications are described, and the motivating factors for the changes are discussed. Most change…

Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures…

Classification systems are necessary in order to provide a framework in which to scientifically study the etiology, pathogenesis, and treatment of diseases in an orderly fashion. In addition, such systems give clinician…

An automatic procedure for recovering a complete crystal structure after a direct phasing process is described. The procedure consists mainly of a Fourier recycling method that can be implemented in any direct-methods p…

7. A. Kurosh, Ringtheoretische Probleme die mit dem Burnsideschen Problem uber periodische Gruppen in Zussammenhang stehen, Bull. Acad. Sei. URSS, Ser. Math. vol. 5 (1941) pp. 233-240. 8. J. Levitzki, On the radical of…

In recent years, members of the protein kinase family have been discovered at an accelerated pace. Most were first described, not through the traditional biochemical approach of protein purification and enzyme assay, bu…

Protein kinase C, an enzyme that is activated by the receptor-mediated hydrolysis of inositol phospholipids, relays information in the form of a variety of extracellular signals across the membrane to regulate many Ca2+…

The author was led to the study given in this paper from a consideration of large scale computing machines in which a large number of operations must be performed without a single error in the end result. This problem o…

BACKGROUND/AIMS: the anti-vascular endothelial growth factors (VEGF), Aflibercept and Ranibizumab, are used for the treatment of macular degeneration. Here we examined the involvement of nitric oxide (NO), mitochondria…

Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure involves administration of a photosensiti…

Institutions are the humanly devised constraints that structure political, economic, and social interaction. They consist of both informal constraints (sanctions, taboos, customs, traditions, and codes of conduct), and…

A new neutral-point-clamped pulsewidth modulation (PWM) inverter composed of main switching devices which operate as switches for PWM and auxiliary switching devices to clamp the output terminal potential to the neutral…

What is the relation between gestures and speech? In terms of symbolic forms, of course, the spontaneous and unwitting gestures we make while talking differ sharply from spoken language itself. Whereas spoken language i…

Resting state functional connectivity reveals intrinsic, spontaneous networks that elucidate the functional architecture of the human brain. However, valid statistical analysis used to identify such networks must addres…

BACKGROUND: The optimal target range for blood glucose in critically ill patients remains unclear. METHODS: Within 24 hours after admission to an intensive care unit (ICU), adults who were expected to require treatment…

BACKGROUND: We have little systematic information about the extent to which standard processes involved in health care--a key element of quality--are delivered in the United States. METHODS: We telephoned a random sampl…

CONTEXT: While recent pharmacological advances have generated increased public interest and demand for clinical services regarding erectile dysfunction, epidemiologic data on sexual dysfunction are relatively scant for…

When a rotating black hole is threaded by magnetic field lines supported by external currents flowing in an equatorial disc, an electric potential difference will be induced. If the field strength is large enough, the v…

Innovationen sind ein Dreh- und Angelpunkt für die Wettbewerbsfähigkeit von Unternehmen, insbesondere in einem dynamischen Wettbewerbsumfeld. Das fundierte Verständnis um die Quellen oder Ursprungsorte von Innovationen…

This paper outlines a new approach to the study of power, that of the sociology of translation. Starting from three principles, those of agnosticism (impartiality between actors engaged in controversy), generalised symm…

Green Chemistry is a relatively new emerging field that strives to work at the molecular level to achieve sustainability. The field has received widespread interest in the past decade due to its ability to harness chemi…

The basic approximations of the MNDO (modified neglect of diatomic overlap) method are described including a semiempirical model for the two-center repulsion integrals. Parametric functions for the various terms in the…

Advances in fields of inquiry as diverse as neuroscience, molecular biology, genomics, developmental psychology, epidemiology, sociology, and economics are catalyzing an important paradigm shift in our understanding of…

Simple interval estimate methods for proportions exhibit poor coverage and can produce evidently inappropriate intervals. Criteria appropriate to the evaluation of various proposed methods include: closeness of the achi…

To evaluate the influence of the angiotensin-converting-enzyme inhibitor enalapril (2.5 to 40 mg per day) on the prognosis of severe congestive heart failure (New York Heart Association [NYHA] functional class IV), we r…

Digital transformation and resultant business model innovation have fundamentally altered consumers’ expectations and behaviors, putting immense pressure on traditional firms, and disrupting numerous markets. Drawing on…

The response styles theory (Nolen-Hoeksema, 1991) was proposed to explain the insidious relationship between rumination and depression. We review the aspects of the response styles theory that have been well-supported,…

The synergistic action of cytosolic Ca2+ and inositol 1,4,5-trisphosphate (InsP3) in releasing intracellular Ca2+ stores has been suggested to be responsible for the complex intracellular Ca2 signals observed during hor…

// Linlin Chen 1, * , Huidan Deng 1, * , Hengmin Cui 1, 2 , Jing Fang 1, 2 , Zhicai Zuo 1, 2 , Junliang Deng 1, 2 , Yinglun Li 1, 2 , Xun Wang 1, 2 and Ling Zhao 1, 2 1 College of Veterinary Medicine, Sichuan Agricultur…

BACKGROUND: The Swedish National Inpatient Register (IPR), also called the Hospital Discharge Register, is a principal source of data for numerous research projects. The IPR is part of the National Patient Register. The…

This bestselling book is a unique introduction to the practice of university teaching and its underlying theory. This new edition has been fully revised and updated in view of the extensive changes which have taken plac…

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Post-1965 immigration to the United States has given rise to a vigorous literature focused on adult newcomers. There is, however, a growing new second generation whose prospects of adaptation cannot be gleaned from the…

BACKGROUND: Modern medicine often clashes with traditional medicine such as Chinese herbal medicine because of the little understanding of the underlying mechanisms of action of the herbs. In an effort to promote integr…

We show that inversion symmetry breaking together with spin-orbit coupling leads to coupled spin and valley physics in monolayers of MoS2 and other group-VI dichalcogenides, making possible controls of spin and valley i…

The first unified account of the theory, methodology, and applications of the EM algorithm and its extensionsSince its inception in 1977, the Expectation-Maximization (EM) algorithm has been the subject of intense scrut…

BACKGROUND: We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor receptor, in the treatment of locoregi…

We present an analysis of atmospheric neutrino data from a 33.0 kton yr (535-day) exposure of the Super-Kamiokande detector. The data exhibit a zenith angle dependent deficit of muon neutrinos which is inconsistent with…

Preface. Introduction. Arrays and Spatial Filters. Synthesis of Linear Arrays and Apertures. Planar Arrays and Apertures. Characterization of Space-Time Processes. Optimum Waveform Estimation. Adaptive Beamformers. Para…

Second and revised edition Understanding Molecular Simulation: From Algorithms to Applications explains the physics behind the recipes of molecular simulation for materials science. Computer simulators are continuously…

A detailed comparison was made of two methods for assessing the features of eating disorders. An investigator-based interview was compared with a self-report questionnaire based directly on that interview. A number of i…

Summary Methods for studying the stability over time of regression relationships are considered. Recursive residuals, defined to be uncorrelated with zero means and constant variance, are introduced and tests based on t…