Top cited papers, continuously indexable.

When mammalian cell cultures or mice are exposed to ionizing radiation in survivable or lethal amounts, novel mass components are found in the histone H2A region of two-dimensional gels. Collectively referred to as gamm…

Metformin is a widely used drug for treatment of type 2 diabetes with no defined cellular mechanism of action. Its glucose-lowering effect results from decreased hepatic glucose production and increased glucose utilizat…

Preface. Introduction. Simple Linear Regression. Multiple Linear Regression. Model Adequacy Checking. Transformations and Weighting to Correct Model Inadequacies. Diagnostics for Leverage and Influence. Polynomial Regre…

Despite widespread adoption in NLP, machine learning models remain mostly black boxes. Understanding the reasons behind predictions is, however, quite important in assessing trust in a model. Trust is fundamental if one…

University of Wisconsin--Madis on Three studies tested basic assumptions derived from a theoretical model based on the dissociation ofantomatic and controlled processes involved in prejudice. Study I supported the model…

Nitrogen is a key element controlling the species composition, diversity, dynamics, and functioning of many terrestrial, freshwater, and marine ecosystems. Many of the original plant species living in these ecosystems a…

This chapter describes the theory of planned behavior (TPB), a prominent reasoned action model, its conceptual foundation, its intellectual history, and the research it has generated. From its roots in propositional con…

BACKGROUND: Although most clinical trials of coronary stents have measured nominally identical safety and effectiveness end points, differences in definitions and timing of assessment have created confusion in interpret…

We undertook this investigation to determine the interrater reliability of manual tests of elbow flexor muscle spasticity graded on a modified Ashworth scale. We each independently graded the elbow flexor muscle spastic…

Freshwater scarcity is increasingly perceived as a global systemic risk. Previous global water scarcity assessments, measuring water scarcity annually, have underestimated experienced water scarcity by failing to captur…

In this paper, we propose a novel explicit image filter called guided filter. Derived from a local linear model, the guided filter computes the filtering output by considering the content of a guidance image, which can…

This article offers objectification theory as a framework for understanding the experiential consequences of being female in a culture that sexually objectifies the female body. Objectification theory posits that girls…

Characteristic patterns of gene expression measured by DNA microarrays have been used to classify tumors into clinically relevant subgroups. In this study, we have refined the previously defined subtypes of breast tumor…

BACKGROUND: Renal function declines progressively in patients who have diabetic nephropathy, and the decline may be slowed by antihypertensive drugs. The purpose of this study was to determine whether captopril has kidn…

The NCEP–DOE Atmospheric Model Intercomparison Project (AMIP-II) reanalysis is a follow-on project to the “50-year” (1948–present) NCEP–NCAR Reanalysis Project. NCEP–DOE AMIP-II re-analysis covers the “20-year” satellit…

An algorithm is presented for the multiple alignment of sequences, either proteins or nucleic acids, that is both accurate and easy to use on microcomputers. The approach is based on the conventional dynamic-programming…

Anecdotal reports indicated that some on-line users were becoming addicted to the Internet in much the same way that others became addicted to drugs or alcohol, which resulted in academic, social, and occupational impai…

Recently developed techniques for estimating bacterial biomass and productivity indicate that bacterial biomass in the sea is related to phytoplankton concentration and that bacteria utilise 10 to 50 % of carbon fixed b…

BACKGROUND: Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potent…

The formation of a dense and uniform thin layer on the substrates is crucial for the fabrication of high-performance perovskite solar cells (PSCs) containing formamidinium with multiple cations and mixed halide anions.…

Examining the correlation between trade and income cannot identify the direction of causation between the two. Countries' geographic characteristics, however, have important effects on trade, and are plausibly uncorrela…

Daniel Kahneman received the Nobel Prize in economics sciences in 2002, December 8, Stockholm, Sweden. This article is the edited version of his Nobel Prize lecture. The author comes back to the problems he has studied…

The Cancer Genome Atlas revealed the genomic landscapes of human cancers. In parallel, immunotherapy is transforming the treatment of advanced cancers. Unfortunately, the majority of patients do not respond to immunothe…

The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acu…

Thermal energy transport by radiation is unique compared to conduction and convection in that a transport medium is not required. In fact, heat transfer by radiation between two surfaces is greater when there is no inte…

In 1978 it was discovered, largely through the work of Fleischmann, Van Duyne, Creighton, and their coworkers that molecules adsorbed on specially prepared silver surfaces produce a Raman spectrum that is at times a mil…

The conservation of sleep across all animal species suggests that sleep serves a vital function. We here report that sleep has a critical function in ensuring metabolic homeostasis. Using real-time assessments of tetram…

The front matter of the December 2011 issue contains the Table of Contents

BACKGROUND: Nivolumab combined with ipilimumab resulted in longer progression-free survival and a higher objective response rate than ipilimumab alone in a phase 3 trial involving patients with advanced melanoma. We now…

BACKGROUND: Cardiac arrest outside the hospital is common and has a poor outcome. Studies in laboratory animals suggest that hypothermia induced shortly after the restoration of spontaneous circulation may improve neuro…

Quality work that fosters job satisfaction and health enjoys top priority in industry all over the world. This was not always so. Until recently analysis of job attitudes focused primarily on human relations problems wi…

Thomas Kuhn’s The Structure of Scientific Revolutions can be seen, without exaggeration, as a landmark text in intellectual history. In his analysis of shifts in scientific thinking, Kuhn questioned the prevailing view…

A new recurrent neural network based language model (RNN LM) with applications to speech recognition is presented. Results indicate that it is possible to obtain around 50% reduction of perplexity by using mixture of se…

PartitionFinder 2 is a program for automatically selecting best-fit partitioning schemes and models of evolution for phylogenetic analyses. PartitionFinder 2 is substantially faster and more efficient than version 1, an…

OBJECTIVES: To gain an understanding of elderly people's fear of falling by exploring the prevalence and determinants of perceived and physiological fall risk and to understand the role of disparities in perceived and p…

Journal Article RELATIONS BETWEEN TWO SETS OF VARIATES Get access HAROLD HOTELLING HAROLD HOTELLING Columbia University Search for other works by this author on: Oxford Academic Google Scholar Biometrika, Volume 28, Iss…

The local density theory is developed by Hohenberg, Kohn and Sham is extended to the spin polarized case. A spin dependent one- electron potential pertinent to ground state properties is obtained from calculations of th…

We have fabricated sonic crystals, based on the idea of localized resonant structures, that exhibit spectral gaps with a lattice constant two orders of magnitude smaller than the relevant wavelength. Disordered composit…

CONTEXT: Between 1980 and 1999, the prevalence of adult obesity (body mass index [BMI] ≥30) increased in the United States and the distribution of BMI changed. More recent data suggested a slowing or leveling off of the…

From Jane Austen to Salman Rushdie, from Yeats to the media coverage of the Gulf War, this is an account of the roots of imperialism in European culture. While many historians and commentators have analyzed the phenomen…

Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not yet available and their charac…

Over the past 30 years, conservation of resources (COR) theory has become one of the most widely cited theories in organizational psychology and organizational behavior. COR theory has been adopted across the many areas…

Entanglement purification protocols (EPPs) and quantum error-correcting codes (QECCs) provide two ways of protecting quantum states from interaction with the environment. In an EPP, perfectly entangled pure states are e…

We derived and tested a short form of the Center for Epidemio-logic Studies Depression Scale (CES-D) for reliability and validity among a sample of well older adults in a large Health Maintenance Organization. The 10-it…

Animal and plant populations often occupy a variety of local areas and may experience different local birth and death rates in different areas. When this occurs, reproductive surpluses from productive source habitats ma…

We address the image denoising problem, where zero-mean white and homogeneous Gaussian additive noise is to be removed from a given image. The approach taken is based on sparse and redundant representations over trained…

Part 1. Overview of Attachment Theory. Cassidy, The Nature of the Child's Ties. Kobak, Madsen, Disruptions in Attachment Bonds: Implications for Theory, Research, and Clinical Intervention. Shaver, Fraley, Attachment, L…

Several parametric representations of the acoustic signal were compared with regard to word recognition performance in a syllable-oriented continuous speech recognition system. The vocabulary included many phonetically…

BACKGROUND: Osimertinib is an oral, third-generation, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that selectively inhibits both EGFR-TKI-sensitizing and EGFR T790M resistance muta…

Critical Discourse Analysis (CDA; better named critical discourse studies [CDS]) is a movement or perspective of multidisciplinary discourse studies that specifically focuses on the discursive reproduction of power abus…

Using 6 longitudinal data sets, the authors estimate links between three key elements of school readiness--school-entry academic, attention, and socioemotional skills--and later school reading and math achievement. In a…

If service quality relates to retention of customers at the aggregate level, as other research has indicated, then evidence of its impact on customers’ behavioral responses should be detectable. The authors offer a conc…

Undoing Gender constitutes Judith Butler's recent reflections on gender and sexuality, focusing on new kinship, psychoanalysis and the incest taboo, transgender, intersex, diagnostic categories, social violence, and the…

BACKGROUND: Patients with chronic kidney disease have a high risk of adverse kidney and cardiovascular outcomes. The effect of dapagliflozin in patients with chronic kidney disease, with or without type 2 diabetes, is n…

Identifying a maximum independent set is a fundamental NP-hard problem. This problem has several real-world applications and requires finding the largest possible set of vertices not adjacent to each other in an undirec…

Damage to the hippocampal system disrupts recent memory but leaves remote memory intact. The account presented here suggests that memories are first stored via synaptic changes in the hippocampal system, that these chan…

Understanding customer experience and the customer journey over time is critical for firms. Customers now interact with firms through myriad touch points in multiple channels and media, and customer experiences are more…

Today's best perovskite solar cells use a mixture of formamidinium and methylammonium as the monovalent cations. With the addition of inorganic cesium, the resulting triple cation perovskite compositions are thermally m…

We discuss the cognitive and the psychophysical determinants of choice in risky and riskless contexts. The psychophysics of value induce risk aversion in the domain of gains and risk seeking in the domain of losses. The…

Neurogenesis in the mammalian central nervous system is believed to end in the period just after birth; in the mouse striatum no new neurons are produced after the first few days after birth. In this study, cells isolat…

Preface. 1 Characteristic Features of Surfactants. A Conditions Under Which Interfacial Phenomena and Surfactants Become Significant. B General Structural Features and Behavior of Surfactants. 1 General Use of Charge Ty…

An expression is derived for the equilibrium free energy difference between two configurations of a system, in terms of an ensemble of finite-time measurements of the work performed in parametrically switching from one…

eggNOG is a public database of orthology relationships, gene evolutionary histories and functional annotations. Here, we present version 5.0, featuring a major update of the underlying genome sets, which have been expan…

Theoretical models predict that overconfident investors trade excessively. We test this prediction by partitioning investors on gender. Psychological research demonstrates that, in areas such as finance, men are more ov…

Advances in processor, memory and radio technology will enable small and cheap nodes capable of sensing, communication and computation. Networks of such nodes can coordinate to perform distributed sensing of environment…

Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16(INK4a) and cyclin D1, protei…