Programmatic discovery

Top cited papers, continuously indexable.

This page pulls one slice of the highest-cited DOI-backed works from OpenAlex and links every result to its branded resea.org DOI page. It exists to create crawl paths, not just a single vanity landing.

The Monte Carlo Method

6176 citations1949Journal of the American Statistical Association
N. Metropolis, Stanislaw M. Ulam

We shall present here the motivation and a general description of a method dealing with a class of problems in mathematical physics. The method is, essentially, a statistical approach to the study of differential equati…

THE GREEN FLUORESCENT PROTEIN

6175 citations1998Annual Review of Biochemistry
Roger Y. Tsien

In just three years, the green fluorescent protein (GFP) from the jellyfish Aequorea victoria has vaulted from obscurity to become one of the most widely studied and exploited proteins in biochemistry and cell biology.…

The Human Microbiome Project

6174 citations2007Nature
Peter J. Turnbaugh, Ruth E. Ley, Micah Hamady, Claire M. Fraser, Rob Knight

A strategy to understand the microbial components of the human genetic and metabolic landscape and how they contribute to normal physiology and predisposition to disease.

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

6171 citations2006Critical Care Medicine
Anand Kumar, Daniel Roberts, Kenneth E. Wood, Bruce Light, Joseph E. Parrillo

OBJECTIVE: To determine the prevalence and impact on mortality of delays in initiation of effective antimicrobial therapy from initial onset of recurrent/persistent hypotension of septic shock. DESIGN: A retrospective c…

Theory of open quantum systems

6171 citations2002The Journal of Chemical Physics
Rui‐Xue Xu, YiJing Yan

A quantum dissipation theory is constructed with the system–bath interaction being treated rigorously at the second-order cumulant level for both reduced dynamics and initial canonical boundary condition. The theory is…

Power-Dependence Relations

6169 citations1962American Sociological Review
Richard M. Emerson

Judging from the frequent occurrence of such words as power, influence, dominance and submission, status and authority, the importance of power is widely recognized, yet considerable confusion exists concerning these co…

Deep Learning with Differential Privacy

6168 citations2016arXiv (Cornell University)
Martı́n Abadi, Andy Chu, Ian Goodfellow, H. Brendan McMahan, Ilya Mironov

Machine learning techniques based on neural networks are achieving remarkable results in a wide variety of domains. Often, the training of models requires large, representative datasets, which may be crowdsourced and co…

Cancer treatment and survivorship statistics, 2016

6168 citations2016CA A Cancer Journal for Clinicians
Kimberly D. Miller, Rebecca L. Siegel, Chun Chieh Lin, Angela B. Mariotto, Joan L. Kramer

The number of cancer survivors continues to increase because of both advances in early detection and treatment and the aging and growth of the population. For the public health community to better serve these survivors,…

Evaluating the Quality of Medical Care

6167 citations2005Milbank Quarterly
Avedis Donabedian

This paper is an attempt to describe andevaluate current methods for assessing the quality of medicalcare and to suggest some directions for further study. It is con-cerned with methods rather than findings, and with an…

Working with Emotional Intelligence

6164 citations1999ETC.: A Review of General Semantics
Daniel Goleman

In Working with Emotional Intelligence,Goleman reveals the skills that distinguish star performers in every field, form entry-level jobs to top executive positions. He shows that the single most important factor is not…

Federated Machine Learning

6163 citations2019ACM Transactions on Intelligent Systems and Technology
Qiang Yang, Yang Liu, Tianjian Chen, Yongxin Tong

Today’s artificial intelligence still faces two major challenges. One is that, in most industries, data exists in the form of isolated islands. The other is the strengthening of data privacy and security. We propose a p…

Toll-Like Receptors

6161 citations2003Annual Review of Immunology
Kiyoshi Takeda, Tsuneyasu Kaisho, Shizuo Akira

The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defense mechanisms. In drosophila antimicrobial…

The Econometrics of Financial Markets

6160 citations2012Princeton University Press eBooks
John Y. Campbell, Andrew W. Lo, A. Craig MacKinlay

This book is an ambitious effort by three well-known and well-respected scholars to fill an acknowledged void in the literature—a text covering the burgeoning field of empirical finance. As the authors note in the prefa…

An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases

6160 citations2007American Journal of Respiratory and Critical Care Medicine
David E. Griffith, Timothy R. Aksamit, Barbara A. Brown‐Elliott, Antonino Catanzaro, Charles L. Daley

Diagnostic Criteria of Nontuberculous Mycobacterial Lung Disease Key Laboratory Features of NTM Health Careand Hygiene-associated Disease Prevention Prophylaxis and Treatment of NTM Disease Introduction Methods Taxonomy…

SENSE: Sensitivity encoding for fast MRI

6159 citations1999Magnetic Resonance in Medicine
Klaas P. Pruessmann, Markus Weiger, Markus B. Scheidegger, Peter Boesiger

New theoretical and practical concepts are presented for considerably enhancing the performance of magnetic resonance imaging (MRI) by means of arrays of multiple receiver coils. Sensitivity encoding (SENSE) is based on…

Optimal Auction Design

6159 citations1981Mathematics of Operations Research
Roger B. Myerson

This paper considers the problem faced by a seller who has a single object to sell to one of several possible buyers, when the seller has imperfect information about how much the buyers might be willing to pay for the o…

The Theory of Open Quantum Systems

6156 citations2007Unknown source
Heinz‐Peter Breuer, Francesco Petruccione

Abstract This book treats the central physical concepts and mathematical techniques used to investigate the dynamics of open quantum systems. To provide a self-contained presentation, the text begins with a survey of cl…

Nonparametric Statistical Methods

6153 citations1999Technometrics

This Second Edition of Myles Hollander and Douglas A. Wolfe's successful Nonparametric Statistical Methods meets the needs of a new generation of users, with completely up-to-date coverage of this important statistical…

Cuckoo Search via Lévy flights

6148 citations2009Unknown source
Xin‐She Yang, Suash Deb

In this paper, we intend to formulate a new meta-heuristic algorithm, called Cuckoo Search (CS), for solving optimization problems. This algorithm is based on the obligate brood parasitic behaviour of some cuckoo specie…

Optimization by Vector Space Methods

6145 citations1970Students Quarterly Journal

From the Publisher: Engineers must make decisions regarding the distribution of expensive resources in a manner that will be economically beneficial. This problem can be realistically formulated and logically analyzed w…

Ethnicity, Insurgency, and Civil War

6136 citations2003American Political Science Review
James D. Fearon, David D. Laitin

An influential conventional wisdom holds that civil wars proliferated rapidly with the end of the Cold War and that the root cause of many or most of these has been ethnic and religious antagonisms. We show that the cur…

Cutaneous Wound Healing

6129 citations1999New England Journal of Medicine
Adam J. Singer, Richard A.F. Clark

The primary function of the skin is to serve as a protective barrier against the environment. Loss of the integrity of large portions of the skin as a result of injury or illness may lead to major disability or even dea…

Political Order in Changing Societies

6123 citations1970Verfassung in Recht und Übersee
Samuel P. Huntington

now-classic examination of the development of viable political institutions in emerging nations is a major and enduring contribution to modern political analysis. In a new Foreword, Francis Fukuyama assesses Huntington'…

Structure-from-Motion Revisited

6122 citations2016Unknown source
Johannes L. Schönberger, Jan‐Michael Frahm

Incremental Structure-from-Motion is a prevalent strategy for 3D reconstruction from unordered image collections. While incremental reconstruction systems have tremendously advanced in all regards, robustness, accuracy,…