Top cited papers, continuously indexable.
This page pulls one slice of the highest-cited DOI-backed works from OpenAlex and links every result to its branded resea.org DOI page. It exists to create crawl paths, not just a single vanity landing.
Missing Data Analysis: Making It Work in the Real World
This review presents a practical summary of the missing data literature, including a sketch of missing data theory and descriptions of normal-model multiple imputation (MI) and maximum likelihood methods. Practical miss…
Rho GTPases and the Actin Cytoskeleton
The actin cytoskeleton mediates a variety of essential biological functions in all eukaryotic cells. In addition to providing a structural framework around which cell shape and polarity are defined, its dynamic properti…
The Monte Carlo Method
We shall present here the motivation and a general description of a method dealing with a class of problems in mathematical physics. The method is, essentially, a statistical approach to the study of differential equati…
THE GREEN FLUORESCENT PROTEIN
In just three years, the green fluorescent protein (GFP) from the jellyfish Aequorea victoria has vaulted from obscurity to become one of the most widely studied and exploited proteins in biochemistry and cell biology.…
Technological Discontinuities and Organizational Environments
The Human Microbiome Project
A strategy to understand the microbial components of the human genetic and metabolic landscape and how they contribute to normal physiology and predisposition to disease.
cclib: A library for package‐independent computational chemistry algorithms
There are now a wide variety of packages for electronic structure calculations, each of which differs in the algorithms implemented and the output format. Many computational chemistry algorithms are only available to us…
The Analysis of Spatial Association by Use of Distance Statistics
Introduced in this paper is a family of statistics, G , that can be used as a measure of spatial association in a number of circumstances. The basic statistic is derived, its properties are identified, and its advantage…
Turbulence and the dynamics of coherent structures. I. Coherent structures
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*
OBJECTIVE: To determine the prevalence and impact on mortality of delays in initiation of effective antimicrobial therapy from initial onset of recurrent/persistent hypotension of septic shock. DESIGN: A retrospective c…
Theory of open quantum systems
A quantum dissipation theory is constructed with the system–bath interaction being treated rigorously at the second-order cumulant level for both reduced dynamics and initial canonical boundary condition. The theory is…
A compendium of neuropsychological tests: administration, norms, and commentary
1. Psychometrics in Neuropsychological Assessment 2. Norms Selection in Neuropsychological Assessment 3. History Taking 4. Test Selection, Test Administration, and Preparation of the Patient 5. Report Writing and Feedba…
Insensitivity to future consequences following damage to human prefrontal cortex
Power-Dependence Relations
Judging from the frequent occurrence of such words as power, influence, dominance and submission, status and authority, the importance of power is widely recognized, yet considerable confusion exists concerning these co…
Deep Learning with Differential Privacy
Machine learning techniques based on neural networks are achieving remarkable results in a wide variety of domains. Often, the training of models requires large, representative datasets, which may be crowdsourced and co…
Cancer treatment and survivorship statistics, 2016
The number of cancer survivors continues to increase because of both advances in early detection and treatment and the aging and growth of the population. For the public health community to better serve these survivors,…
Evaluating the Quality of Medical Care
This paper is an attempt to describe andevaluate current methods for assessing the quality of medicalcare and to suggest some directions for further study. It is con-cerned with methods rather than findings, and with an…
Approximation capabilities of multilayer feedforward networks
Association of Official Analytical Chemists: 1964–1988
Bootstrap Methods for Standard Errors, Confidence Intervals, and Other Measures of Statistical Accuracy
This is a review of bootstrap methods, concentrating on basic ideas and applications rather than theoretical considerations. It begins with an exposition of the bootstrap estimate of standard error for one-sample situat…
Working with Emotional Intelligence
In Working with Emotional Intelligence,Goleman reveals the skills that distinguish star performers in every field, form entry-level jobs to top executive positions. He shows that the single most important factor is not…
Federated Machine Learning
Today’s artificial intelligence still faces two major challenges. One is that, in most industries, data exists in the form of isolated islands. The other is the strengthening of data privacy and security. We propose a p…
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
Toll-Like Receptors
The innate immune system in drosophila and mammals senses the invasion of microorganisms using the family of Toll receptors, stimulation of which initiates a range of host defense mechanisms. In drosophila antimicrobial…
The Econometrics of Financial Markets
This book is an ambitious effort by three well-known and well-respected scholars to fill an acknowledged void in the literature—a text covering the burgeoning field of empirical finance. As the authors note in the prefa…
An Official ATS/IDSA Statement: Diagnosis, Treatment, and Prevention of Nontuberculous Mycobacterial Diseases
Diagnostic Criteria of Nontuberculous Mycobacterial Lung Disease Key Laboratory Features of NTM Health Careand Hygiene-associated Disease Prevention Prophylaxis and Treatment of NTM Disease Introduction Methods Taxonomy…
Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis
BACKGROUND: Drotrecogin alfa (activated), or recombinant human activated protein C, has antithrombotic, antiinflammatory, and profibrinolytic properties. In a previous study, drotrecogin alfa activated produced dose-dep…
SAGE Handbook of Mixed Methods in Social & Behavioral Research
Part 1 The Research Enterprise in the Social and Behavioral Sciences: Then and Now Ch 1 Major Issues and Controversies in the Use of Methods in the Social and Behavioral Sciences - Charles Teddlie, Abbas Tashakkori Ch 2…
Knowledge Management: An Organizational Capabilities Perspective
A hallmark of the new economy is the ability of organizations to realize economic value from their collection of knowledge assets as well as their assets of information, production distribution, and affiliation. Despite…
SENSE: Sensitivity encoding for fast MRI
New theoretical and practical concepts are presented for considerably enhancing the performance of magnetic resonance imaging (MRI) by means of arrays of multiple receiver coils. Sensitivity encoding (SENSE) is based on…
Computer Visualization of Three-Dimensional Image Data Using IMOD
Solitons, Nonlinear Evolution Equations and Inverse Scattering
Solitons have been of considerable interest to mathematicians since their discovery by Kruskal and Zabusky. This book brings together several aspects of soliton theory currently only available in research papers. Emphas…
Optimal Auction Design
This paper considers the problem faced by a seller who has a single object to sell to one of several possible buyers, when the seller has imperfect information about how much the buyers might be willing to pay for the o…
Antithrombotic Therapy for VTE Disease
The Theory of Open Quantum Systems
Abstract This book treats the central physical concepts and mathematical techniques used to investigate the dynamics of open quantum systems. To provide a self-contained presentation, the text begins with a survey of cl…
The Nature and Properties of Soils
Quantum Spin Hall Insulator State in HgTe Quantum Wells
Recent theory predicted that the quantum spin Hall effect, a fundamentally new quantum state of matter that exists at zero external magnetic field, may be realized in HgTe/(Hg,Cd)Te quantum wells. We fabricated such sam…
A novel genetic system to detect protein–protein interactions
An improved algorithm for reaction path following
A new algorithm is presented for obtaining points on a steepest descent path from the transition state of the reactants and products. In mass-weighted coordinates, this path corresponds to the intrinsic reaction coordin…
Option pricing when underlying stock returns are discontinuous
A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study
Objective. —To develop and validate a new Simplified Acute Physiology Score, the SAPS II, from a large sample of surgical and medical patients, and to provide a method to convert the score to a probability of hospital m…
TARGET ARTICLE: "Posttraumatic Growth: Conceptual Foundations and Empirical Evidence"
This article describes the concept of posttraumatic growth, its conceptual foundations, and supporting empirical evidence. Posttraumatic growth is the experience of positive change that occurs as a result of the struggl…
BIOTIC INVASIONS: CAUSES, EPIDEMIOLOGY, GLOBAL CONSEQUENCES, AND CONTROL
Biotic invaders are species that establish a new range in which they proliferate, spread, and persist to the detriment of the environment. They are the most important ecological outcomes from the unprecedented alteratio…
Nonparametric Statistical Methods
This Second Edition of Myles Hollander and Douglas A. Wolfe's successful Nonparametric Statistical Methods meets the needs of a new generation of users, with completely up-to-date coverage of this important statistical…
The incidence of congenital heart disease
BoltzTraP. A code for calculating band-structure dependent quantities
The contribution of outdoor air pollution sources to premature mortality on a global scale
Parkinson's disease
Cuckoo Search via Lévy flights
In this paper, we intend to formulate a new meta-heuristic algorithm, called Cuckoo Search (CS), for solving optimization problems. This algorithm is based on the obligate brood parasitic behaviour of some cuckoo specie…
Generalized impulse response analysis in linear multivariate models
Scaling Theory of Localization: Absence of Quantum Diffusion in Two Dimensions
Arguments are presented that the $T=0$ conductance $G$ of a disordered electronic system depends on its length scale $L$ in a universal manner. Asymptotic forms are obtained for the scaling function $\ensuremath{\beta}(…
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
Since the 1990 NIH-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by…
Selective Search for Object Recognition
A solution to Plato's problem: The latent semantic analysis theory of acquisition, induction, and representation of knowledge.
How do people know as much as they do with as little information as they get? The problem takes many forms; learning vocabulary from text is an especially dramatic and convenient case for research. A new general theory…
Handbook of research on mathematics teaching and learning
Optimization by Vector Space Methods
From the Publisher: Engineers must make decisions regarding the distribution of expensive resources in a manner that will be economically beneficial. This problem can be realistically formulated and logically analyzed w…
General Methods for Monitoring Convergence of Iterative Simulations
We generalize the method proposed by Gelman and Rubin (1992a) for monitoring the convergence of iterative simulations by comparing between and within variances of multiple chains, in order to obtain a family of tests fo…
Business Intelligence and Analytics: From Big Data to Big Impact
Business intelligence and analytics (BI&A) has emerged as an important area of study for both practitioners and researchers, reflecting the magnitude and impact of data-related problems to be solved in contemporary busi…
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
A numerical approach to the testing of the fission hypothesis
A finite-size particle scheme for the numerical solution of twoand three-dimensional gasdynamic problems of astronomical interest is described and tested. The scheme is then applied to the fission problem for optically…
Influence of diet on the distribution of nitrogen isotopes in animals
Participation and Democratic Theory
Shows that current elitist theories are based on an inadequate understanding of the early writings of democratic theory and that much sociological evidence has been ignored.
Carbon-Based Supercapacitors Produced by Activation of Graphene
Supercapacitors, also called ultracapacitors or electrochemical capacitors, store electrical charge on high-surface-area conducting materials. Their widespread use is limited by their low energy storage density and rela…
Accumulation and fragmentation of plastic debris in global environments
One of the most ubiquitous and long-lasting recent changes to the surface of our planet is the accumulation and fragmentation of plastics. Within just a few decades since mass production of plastic products commenced in…
Ethnicity, Insurgency, and Civil War
An influential conventional wisdom holds that civil wars proliferated rapidly with the end of the Cold War and that the root cause of many or most of these has been ethnic and religious antagonisms. We show that the cur…
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
BACKGROUND: Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT…
Cross-cultural adaptation of health-related quality of life measures: Literature review and proposed guidelines
Taking the Human Out of the Loop: A Review of Bayesian Optimization
Big Data applications are typically associated with systems involving large numbers of users, massive complex software systems, and large-scale heterogeneous computing and storage architectures. The construction of such…
Understanding individual human mobility patterns
Breaking the diffraction resolution limit by stimulated emission: stimulated-emission-depletion fluorescence microscopy
We propose a new type of scanning fluorescence microscope capable of resolving 35 nm in the far field. We overcome the diffraction resolution limit by employing stimulated emission to inhibit the fluorescence process in…
The Colonial Origins of Comparative Development: An Empirical Investigation: Reply
Acemoglu, Johnson, and Robinson (2001) established that economic institutions today are correlated with expected mortality of European colonialists. David Albouy argues this relationship is not robust. He drops all data…
The DNA-damage response in human biology and disease
MEGA2: molecular evolutionary genetics analysis software
UNLABELLED: We have developed a new software package, Molecular Evolutionary Genetics Analysis version 2 (MEGA2), for exploring and analyzing aligned DNA or protein sequences from an evolutionary perspective. MEGA2 vast…
The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
RELION, for REgularized LIkelihood OptimizatioN, is an open-source computer program for the refinement of macromolecular structures by single-particle analysis of electron cryo-microscopy (cryo-EM) data. Whereas alterna…
Automated electron microscope tomography using robust prediction of specimen movements
MapChart: Software for the Graphical Presentation of Linkage Maps and QTLs
Over the last 15 years a wealth of linkage maps and quantitative trait loci (QTL) mapping results have become available. The pace of generating this genetic information is accelerating owing to advances in molecular mar…
CDK inhibitors: positive and negative regulators of G1-phase progression
Mitogen-dependent progression through the first gap phase (G1) and initiation of DNA synthesis (S phase) during the mammalian cell division cycle are cooperatively regulated by several classes of cyclin-dependent kinase…
Cutaneous Wound Healing
The primary function of the skin is to serve as a protective barrier against the environment. Loss of the integrity of large portions of the skin as a result of injury or illness may lead to major disability or even dea…
Designing Qualitative Research
AKT/PKB Signaling: Navigating Downstream
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
Through the study of transcriptional activation in response to interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma), a previously unrecognized direct signal transduction pathway to the nucleus has been uncovere…
Inositol trisphosphate, a novel second messenger in cellular signal transduction
Monodisperse FePt Nanoparticles and Ferromagnetic FePt Nanocrystal Superlattices
Synthesis of monodisperse iron-platinum (FePt) nanoparticles by reduction of platinum acetylacetonate and decomposition of iron pentacarbonyl in the presence of oleic acid and oleyl amine stabilizers is reported. The Fe…
The cochrane database of systematic reviews
Silver nanoparticles as a new generation of antimicrobials
Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association
BACKGROUND: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, inclu…
Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010
Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain
The relationship between return and market value of common stocks
Political Order in Changing Societies
now-classic examination of the development of viable political institutions in emerging nations is a major and enduring contribution to modern political analysis. In a new Foreword, Francis Fukuyama assesses Huntington'…
Structure-from-Motion Revisited
Incremental Structure-from-Motion is a prevalent strategy for 3D reconstruction from unordered image collections. While incremental reconstruction systems have tremendously advanced in all regards, robustness, accuracy,…
Applications of lie groups to differential equations
Estimating and Testing Linear Models with Multiple Structural Changes
This paper develops the statistical theory for testing and estimating multiple change points in regression models. The rate of convergence and limiting distribution for the estimated parameters are obtained. Several tes…
GSAS-II : the genesis of a modern open-source all purpose crystallography software package
The newly developed GSAS-II software is a general purpose package for data reduction, structure solution and structure refinement that can be used with both single-crystal and powder diffraction data from both neutron a…
Localized Surface Plasmon Resonance Spectroscopy and Sensing
Localized surface plasmon resonance (LSPR) spectroscopy of metallic nanoparticles is a powerful technique for chemical and biological sensing experiments. Moreover, the LSPR is responsible for the electromagnetic-field…
A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1
A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast and ovarian cancer, has been identified by positional cloning methods. Probable predisposing mutations have been detected in fi…
The analysis of linear partial differential operators
Radiative forcing by long‐lived greenhouse gases: Calculations with the AER radiative transfer models
A primary component of the observed recent climate change is the radiative forcing from increased concentrations of long‐lived greenhouse gases (LLGHGs). Effective simulation of anthropogenic climate change by general c…