<i>The Structure of Scientific Revolutions</i>
35549 citations1963Physics Today
Thomas Kühn, Richard Schlegel
A good book may have the power to change the way we see the world, but a great book actually becomes part of our daily consciousness, pervading our thinking to the point that we take it for granted, and we forget how pr…
Self-efficacy: Toward a unifying theory of behavioral change.
35544 citations1977Psychological Review
Albert Bandura
The present article presents an integrative theoretical framework to explain and to predict psychological changes achieved by different modes of treatment. This theory states that psychological procedures, whatever thei…
Nonparametric Statistics for the Behavioral Sciences
35505 citations1958Revue économique
Henri Guitton, Sidney Siegel
This is the revision of the classic text in the field, adding two new chapters and thoroughly updating all others. The original structure is retained, and the book continues to serve as a combined text/reference.
Biostatistical Analysis
35450 citations1996Ecology
William H. Baltosser, Jerrold H. Zar
AMPLIFICATION AND DIRECT SEQUENCING OF FUNGAL RIBOSOMAL RNA GENES FOR PHYLOGENETICS
35194 citations1990Elsevier eBooks
T. J. White, Thomas D. Bruns, Steven Lee, John W. Taylor
A new mathematical model for relative quantification in real-time RT-PCR
34929 citations2001Nucleic Acids Research
Michael W. Pfaffl
Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to becoming a routine tool in molecular biology to study low abundance gene expression. Real-time…
MicroRNAs
34882 citations2004Cell
David P. Bartel
The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research
34824 citations1989Psychiatry Research
Daniel J. Buysse, Charles F. Reynolds, T. H. Monk, Susan Berman, D J Kupfer
Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being.
34672 citations2000American Psychologist
Richard M. Ryan, Edward L. Deci
Absorptive Capacity: A New Perspective on Learning and Innovation
34634 citations1990Administrative Science Quarterly
Wesley M. Cohen, Daniel A. Levinthal
Wesley M. Cohen, Daniel A. Levinthal, Absorptive Capacity: A New Perspective on Learning and Innovation, Administrative Science Quarterly, Vol. 35, No. 1, Special Issue: Technology, Organizations, and Innovation (Mar.,…
Naturalistic inquiry
34475 citations1985International Journal of Intercultural Relations
Yvonna S. Lincoln, Egon G. Guba, Joseph J. Pilotta
RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
34380 citations2014Bioinformatics
Alexandros Stamatakis
Abstract Motivation: Phylogenies are increasingly used in all fields of medical and biological research. Moreover, because of the next-generation sequencing revolution, datasets used for conducting phylogenetic analyses…
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
34311 citations2011BMJ
Julian P. T. Higgins, Doug Altman, Peter C Gøtzsche, Peter Jüni, David Moher
Flaws in the design, conduct, analysis, and reporting of randomised trials can cause the effect of an intervention to be underestimated or overestimated. The Cochrane Collaboration’s tool for assessing risk of bias aims…
Inference of Population Structure Using Multilocus Genotype Data
34309 citations2000Genetics
Jonathan K. Pritchard, Matthew Stephens, Peter Donnelly
We describe a model-based clustering method for using multilocus genotype data to infer population structure and assign individuals to populations. We assume a model in which there are K populations (where K may be unkn…
The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
34143 citations2012Nucleic Acids Research
Christian Quast, Elmar Pruesse, Pelin Yilmaz, Jan Gerken, Timmy Schweer
SILVA (from Latin silva, forest, http://www.arb-silva.de) is a comprehensive web resource for up to date, quality-controlled databases of aligned ribosomal RNA (rRNA) gene sequences from the Bacteria, Archaea and Eukary…
A new criterion for assessing discriminant validity in variance-based structural equation modeling
34124 citations2014Journal of the Academy of Marketing Science
Jörg Henseler, Christian M. Ringle, Marko Sarstedt
Discriminant validity assessment has become a generally accepted prerequisite for analyzing relationships between latent variables. For variance-based structural equation modeling, such as partial least squares, the For…
Glove: Global Vectors for Word Representation
33801 citations2014Unknown source
Jeffrey Pennington, Richard Socher, Christopher D. Manning
Recent methods for learning vector space representations of words have succeeded in capturing fine-grained semantic and syntactic regularities using vector arith-metic, but the origin of these regularities has remained…
Electrochemical Photolysis of Water at a Semiconductor Electrode
33715 citations1972Nature
Akira Fujishima, Kenichi Honda
[20] Processing of X-ray diffraction data collected in oscillation mode
33602 citations1997Methods in enzymology on CD-ROM/Methods in enzymology
Zbyszek Otwinowski, W. Minor
Support-Vector Networks
33184 citations1995Machine Learning
Corinna Cortes, Vladimir Vapnik
Prospect theory: An analysis of decision under risk
33027 citations1988Cambridge University Press eBooks
Daniel Kahneman, Amos Tversky
Expected utility theory has dominated the analysis of decision making under risk. It has been generally accepted as a normative model of rational choice (Keeney and Raiffa, 1976), and widely applied as a descriptive mod…
ggplot2
32922 citations2016Use R!
Hadley Wickham
Some Tests of Specification for Panel Data: Monte Carlo Evidence and an Application to Employment Equations
32904 citations1991The Review of Economic Studies
Manuel Arellano, Stephen Bond
This paper presents specification tests that are applicable after estimating a dynamic model from panel data by the generalized method of moments (GMM), and studies the practical performance of these procedures using bo…
Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models
32842 citations2008Behavior Research Methods
Kristopher J. Preacher, Andrew F. Hayes
Detection of specific sequences among DNA fragments separated by gel electrophoresis
32832 citations1975Journal of Molecular Biology
E.M. Southern
A RATING SCALE FOR DEPRESSION
32674 citations1960Journal of Neurology Neurosurgery & Psychiatry
M. Hamilton
Untitled work
32644 citations2019Unknown source
Jacob Devlin, Ming‐Wei Chang, Kenton Lee, Kristina Toutanova
Jacob Devlin, Ming-Wei Chang, Kenton Lee, Kristina Toutanova. Proceedings of the 2019 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, Volume 1 (Lon…
A Global Measure of Perceived Stress
32521 citations1983Journal of Health and Social Behavior
Sheldon Cohen, Tom Kamarck, Robin Mermelstein
This paper presents evidence from three samples, two of college students and one of participants in a community smoking-cessation program, for the reliability and validity of a 14-item instrument, the Perceived Stress S…
Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
32500 citations1972Clinical Chemistry
William T. Friedewald, Robert I. Levy, Donald S. Fredrickson
Abstract A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-…
KEGG: Kyoto Encyclopedia of Genes and Genomes
32435 citations1999Nucleic Acids Research
Hiroyuki Ogata, Susumu Goto, Kazushige Sato, Wataru Fujibuchi, Hidemasa Bono
Kyoto Encyclopedia of Genes and Genomes (KEGG) is a knowledge base for systematic analysis of gene functions in terms of the networks of genes and molecules. The major component of KEGG is the PATHWAY database that cons…
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
32379 citations2015Genetics in Medicine
Sue Richards, Nazneen Aziz, Sherri J. Bale, David Bick, Soma Das
Stress, appraisal, and coping
32343 citations1985Behaviour Research and Therapy
H.J. Eysenck
The "What" and "Why" of Goal Pursuits: Human Needs and the Self-Determination of Behavior
32307 citations2000Psychological Inquiry
Edward L. Deci, Richard M. Ryan
Abstract Self-determination theory (SDT) maintains that an understanding of human motivation requires a consideration of innate psychological needs for competence, autonomy, and relatedness. We discuss the SDT concept o…
Development and validation of brief measures of positive and negative affect: The PANAS scales.
32200 citations1988Journal of Personality and Social Psychology
David Watson, Lee Anna Clark, Auke Tellegen
Situated Learning
32168 citations1991Cambridge University Press eBooks
Jean Lave, Étienne Wenger
In this important theoretical treatist, Jean Lave, anthropologist, and Etienne Wenger, computer scientist, push forward the notion of situated learning - that learning is fundamentally a social process. The authors main…
Co-Integration and Error Correction: Representation, Estimation, and Testing
31976 citations1987Econometrica
Robert F. Engle, C. W. J. Granger
The relationship between co-integration and error correction models, first suggested in Granger (1981), is here extended and used to develop estimation procedures, tests, and empirical examples. If each element of a vec…
Histograms of Oriented Gradients for Human Detection
31914 citations2005HAL (Le Centre pour la Communication Scientifique Directe)
Navneet Dalal, Bill Triggs
We study the question of feature sets for robust visual object recognition; adopting linear SVM based human detection as a test case. After reviewing existing edge and gradient based descriptors, we show experimentally…
Gaussian basis sets for use in correlated molecular calculations. I. The atoms boron through neon and hydrogen
31788 citations1989The Journal of Chemical Physics
Thom H. Dunning
In the past, basis sets for use in correlated molecular calculations have largely been taken from single configuration calculations. Recently, Almlöf, Taylor, and co-workers have found that basis sets of natural orbital…
Rich Feature Hierarchies for Accurate Object Detection and Semantic Segmentation
31776 citations2014Unknown source
Ross Girshick, Jeff Donahue, Trevor Darrell, Jitendra Malik
Object detection performance, as measured on the canonical PASCAL VOC dataset, has plateaued in the last few years. The best-performing methods are complex ensemble systems that typically combine multiple low-level imag…
<i>OLEX2</i>: a complete structure solution, refinement and analysis program
31694 citations2009Journal of Applied Crystallography
Oleg V. Dolomanov, Luc J. Bourhis, Richard J. Gildea, Judith A. K. Howard, Horst Puschmann
New software, OLEX2 , has been developed for the determination, visualization and analysis of molecular crystal structures. The software has a portable mouse-driven workflow-oriented and fully comprehensive graphical us…
A Brief Measure for Assessing Generalized Anxiety Disorder
31673 citations2006Archives of Internal Medicine
Robert L. Spitzer, Kurt Kroenke, Janet B. W. Williams, Bernd Löwe
BACKGROUND: Generalized anxiety disorder (GAD) is one of the most common mental disorders; however, there is no brief clinical measure for assessing GAD. The objective of this study was to develop a brief self-report sc…
Development and validation of brief measures of positive and negative affect: The PANAS scales.
31666 citations1988Journal of Personality and Social Psychology
David Watson, Lee A. Clark, Auke Tellegen
In recent studies of the structure of affect, positive and negative affect have consistently emerged as two dominant and relatively independent dimensions. A number of mood scales have been created to measure these fact…
Dynamic capabilities and strategic management
31596 citations1997Strategic Management Journal
David J. Teece, Gary P. Pisano, Amy Shuen
The dynamic capabilities framework analyzes the sources and methods of wealth creation and capture by private enterprise firms operating in environments of rapid technological change. The competitive advantage of firms…
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
31489 citations1985Diabetologia
David R. Matthews, J P Hosker, A. Rudenski, B A Naylor, DF Treacher
<i>Coot</i>: model-building tools for molecular graphics
31476 citations2004Acta Crystallographica Section D Biological Crystallography
Paul Emsley, Kevin Cowtan
CCP4mg is a project that aims to provide a general-purpose tool for structural biologists, providing tools for X-ray structure solution, structure comparison and analysis, and publication-quality graphics. The map-fitti…
SMOTE: Synthetic Minority Over-sampling Technique
31333 citations2002Journal of Artificial Intelligence Research
Nitesh V. Chawla, Kevin W. Bowyer, Lawrence Hall, W. Philip Kegelmeyer
An approach to the construction of classifiers from imbalanced datasets is described. A dataset is imbalanced if the classification categories are not approximately equally represented. Often real-world data sets are pr…
Biodiversity hotspots for conservation priorities
31282 citations2000Nature
Norman Myers, Russell A. Mittermeier, Cristina G. Mittermeier, Gustavo A. B. da Fonseca, Jennifer Kent
Convex Optimization
31266 citations2004Cambridge University Press eBooks
Stephen Boyd, Lieven Vandenberghe
Convex optimization problems arise frequently in many different fields. This book provides a comprehensive introduction to the subject, and shows in detail how such problems can be solved numerically with great efficien…
Clinical Characteristics of Coronavirus Disease 2019 in China
31167 citations2020New England Journal of Medicine
Wei‐jie Guan, Zhengyi Ni, Yu Hu, Wenhua Liang, Chun‐Quan Ou
BACKGROUND: Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. METHOD…
RoB 2: a revised tool for assessing risk of bias in randomised trials
31073 citations2019BMJ
Jonathan A C Sterne, Jelena Savović, Matthew J. Page, Roy G. Elbers, Natalie Blencowe
Assessment of risk of bias is regarded as an essential component of a systematic review on the effects of an intervention. The most commonly used tool for randomised trials is the Cochrane risk-of-bias tool. We updated…
A New Approach to Linear Filtering and Prediction Problems
31049 citations1960Journal of Basic Engineering
R. E. Kalman
The classical filtering and prediction problem is re-examined using the Bode-Shannon representation of random processes and the “state-transition” method of analysis of dynamic systems. New results are: (1) The formulat…
Molecular dynamics with coupling to an external bath
31031 citations1984The Journal of Chemical Physics
Herman J. C. Berendsen, Johan P. M. Postma, Wilfred F. van Gunsteren, A. DiNola, J.R. Haak
In molecular dynamics (MD) simulations the need often arises to maintain such parameters as temperature or pressure rather than energy and volume, or to impose gradients for studying transport properties in nonequilibri…
The central role of the propensity score in observational studies for causal effects
31030 citations1983Biometrika
Paul R. Rosenbaum, Donald B. Rubin
The propensity score is the conditional probability of assignment to a particular treatment given a vector of observed covariates. Both large and small sample theory show that adjustment for the scalar propensity score…
Institutions, Institutional Change and Economic Performance
31017 citations1990Cambridge University Press eBooks
Douglass C. North
Continuing his groundbreaking analysis of economic structures, Douglass North develops an analytical framework for explaining the ways in which institutions and institutional change affect the performance of economies,…
Learning representations by back-propagating errors
31000 citations1986Nature
David E. Rumelhart, Geoffrey E. Hinton, Ronald J. Williams
Rethinking the Inception Architecture for Computer Vision
30988 citations2016Unknown source
Christian Szegedy, Vincent Vanhoucke, Sergey Ioffe, Jon Shlens, Zbigniew Wojna
Convolutional networks are at the core of most state of-the-art computer vision solutions for a wide variety of tasks. Since 2014 very deep convolutional networks started to become mainstream, yielding substantial gains…
Classification of Surgical Complications
30965 citations2004Annals of Surgery
Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien
In Brief Objective: Although quality assessment is gaining increasing attention, there is still no consensus on how to define and grade postoperative complications. This shortcoming hampers comparison of outcome data am…
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
30918 citations2016Breast Care
Andreas D. Hartkopf, Florin‐Andrei Taran, Markus Wallwiener, Christina B. Walter, Bernhard Krämer
Immune checkpoint inhibition represents a major recent breakthrough in the treatment of malignant diseases including breast cancer. Blocking the programmed death receptor-1 (PD-1) and its ligand, PD-L1, has shown impres…
Semiempirical GGA‐type density functional constructed with a long‐range dispersion correction
30829 citations2006Journal of Computational Chemistry
Stefan Grimme
A new density functional (DF) of the generalized gradient approximation (GGA) type for general chemistry applications termed B97-D is proposed. It is based on Becke's power-series ansatz from 1997 and is explicitly para…
Particle mesh Ewald: An <i>N</i>⋅log(<i>N</i>) method for Ewald sums in large systems
30748 citations1993The Journal of Chemical Physics
Tom Darden, Darrin M. York, Lee G. Pedersen
An N⋅log(N) method for evaluating electrostatic energies and forces of large periodic systems is presented. The method is based on interpolation of the reciprocal space Ewald sums and evaluation of the resulting convolu…
Molecular Cloning. A Laboratory Manual
30627 citations1983Biochemical Education
EJ Wood
The ERA5 global reanalysis
30591 citations2020Quarterly Journal of the Royal Meteorological Society
Hans Hersbach, Bill Bell, Paul Berrisford, Shoji Hirahara, Ándrás Horányi
Abstract Within the Copernicus Climate Change Service (C3S), ECMWF is producing the ERA5 reanalysis which, once completed, will embody a detailed record of the global atmosphere, land surface and ocean waves from 1950 o…
BEDTools: a flexible suite of utilities for comparing genomic features
30537 citations2010Bioinformatics
Aaron R. Quinlan, Ira M. Hall
MOTIVATION: Testing for correlations between different sets of genomic features is a fundamental task in genomics research. However, searching for overlaps between features with existing web-based methods is complicated…
An Algorithm for Least-Squares Estimation of Nonlinear Parameters
30457 citations1963Journal of the Society for Industrial and Applied Mathematics
Donald W. Marquardt
Previous article Next article An Algorithm for Least-Squares Estimation of Nonlinear ParametersDonald W. MarquardtDonald W. Marquardthttps://doi.org/10.1137/0111030PDFPDF PLUSBibTexSections ToolsAdd to favoritesExport C…
Matrix Computations
30423 citations2012Johns Hopkins University Press eBooks
Gene H. Golub
A Novel Coronavirus from Patients with Pneumonia in China, 2019
30387 citations2020New England Journal of Medicine
Na Zhu, Dingyu Zhang, Wenling Wang, Xingwang Li, Bo Yang
In December 2019, a cluster of patients with pneumonia of unknown cause was linked to a seafood wholesale market in Wuhan, China. A previously unknown betacoronavirus was discovered through the use of unbiased sequencin…
Swin Transformer: Hierarchical Vision Transformer using Shifted Windows
30265 citations20212021 IEEE/CVF International Conference on Computer Vision (ICCV)
Ze Liu, Yutong Lin, Yue Cao, Han Hu, Yixuan Wei
This paper presents a new vision Transformer, called Swin Transformer, that capably serves as a general-purpose backbone for computer vision. Challenges in adapting Transformer from language to vision arise from differe…
Standard Methods for the Examination of Water and Wastewater
30207 citations1982Water Research
S.H. Jenkins
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
30085 citations2010Genome Research
Aaron McKenna, Matthew G. Hanna, Eric Banks, Andrey Sivachenko, Kristian Cibulskis
Next-generation DNA sequencing (NGS) projects, such as the 1000 Genomes Project, are already revolutionizing our understanding of genetic variation among individuals. However, the massive data sets generated by NGS--the…
Human-level control through deep reinforcement learning
30079 citations2015Nature
Volodymyr Mnih, Koray Kavukcuoglu, David Silver, Andrei A. Rusu, Joel Veness
Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy
30075 citations2005Physical Chemistry Chemical Physics
Florian Weigend, Reinhart Ahlrichs
Gaussian basis sets of quadruple zeta valence quality for Rb-Rn are presented, as well as bases of split valence and triple zeta valence quality for H-Rn. The latter were obtained by (partly) modifying bases developed p…
The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals
30053 citations2007Theoretical Chemistry Accounts
Yan Zhao, Donald G. Truhlar
We present two new hybrid meta exchange- correlation functionals, called M06 and M06-2X. The M06 functional is parametrized including both transition metals and nonmetals, whereas the M06-2X functional is a high-nonloca…
An introduction to probability theory and its applications
29966 citations1958Journal of the Franklin Institute
fastp: an ultra-fast all-in-one FASTQ preprocessor
29939 citations2018Bioinformatics
Shifu Chen, Yanqing Zhou, Yaru Chen, Jia Gu
Motivation: Quality control and preprocessing of FASTQ files are essential to providing clean data for downstream analysis. Traditionally, a different tool is used for each operation, such as quality control, adapter tr…
The MOS 36-ltem Short-Form Health Survey (SF-36)
29847 citations1992Medical Care
John E. Ware, Cathy D. Sherbourne
A 36-item short-form (SF-36) was constructed to survey health status in the Medical Outcomes Study. The SF-36 was designed for use in clinical practice and research, health policy evaluations, and general population sur…
A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences
29840 citations1980Journal of Molecular Evolution
Motoo Kimura
Preparation of Graphitic Oxide
29752 citations1958Journal of the American Chemical Society
William S. Hummers, Richard E. Offeman
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of Graphitic OxideWilliam S. Hummers Jr. and Richard E. OffemanCite this: J. Am. Chem. Soc. 1958, 80, 6, 1339Publication Date (Print):March 1, 1958Publication Hist…
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
29696 citations2017Kidney & Blood Pressure Research
Ömer Toprak, Hüseyin Kurt, Yasin Sarı, Cihat Şarkış, Halil Us
<b><i>Background/Aims:</i></b> Magnesium is an essential mineral for many metabolic functions. There is very little information on the effect of magnesium supplementation on metabolic profiles of…
Features and development of <i>Coot</i>
29671 citations2010Acta Crystallographica Section D Biological Crystallography
Paul Emsley, Bernhard Lohkamp, W. G. Scott, Kevin Cowtan
Coot is a molecular-graphics application for model building and validation of biological macromolecules. The program displays electron-density maps and atomic models and allows model manipulations such as idealization,…
World Medical Association Declaration of Helsinki
29578 citations2013JAMA
1. The World Medical Association (WMA) has developed the Declaration of Helsinki as a statement of ethical principles for medical research involving human subjects, including research on identifiable human material and…
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
29540 citations2008European Journal of Cancer
E. Eisenhauer, P. Therasse, Jan Bogaerts, Lawrence H. Schwartz, Daniel J. Sargent
The Pricing of Options and Corporate Liabilities
29460 citations1973Journal of Political Economy
Fischer Black, Myron S. Scholes
If options are correctly priced in the market, it should not be possible to make sure profits by creating portfolios of long and short positions in options and their underlying stocks. Using this principle, a theoretica…
Basics of Qualitative Research: Grounded Theory Procedures and Techniques.
29443 citations1992Contemporary Sociology A Journal of Reviews
Carolyn Ellis, Anselm Strauss, Juliet Corbin
Introduction Getting Started Theoretical Sensitivity The Uses of Literature Open Coding Techniques for Enhancing Theoretical Sensitivity Axial Coding Selective Coding Process The Conditional Matrix Theoretical Sampling…
MrBayes 3: Bayesian phylogenetic inference under mixed models
29387 citations2003Bioinformatics
Fredrik Ronquist, John P. Huelsenbeck
Abstract Summary: MrBayes 3 performs Bayesian phylogenetic analysis combining information from different data partitions or subsets evolving under different stochastic evolutionary models. This allows the user to analyz…
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
29333 citations2013Bioinformatics
Yang Liao, Gordon K. Smyth, Wei Shi
MOTIVATION: Next-generation sequencing technologies generate millions of short sequence reads, which are usually aligned to a reference genome. In many applications, the key information required for downstream analysis…
WGCNA: an R package for weighted correlation network analysis
29279 citations2008BMC Bioinformatics
Peter Langfelder, Steve Horvath
BACKGROUND: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method for describing the correlation patterns…
Society and the Adolescent Self-Image
29267 citations1965Princeton University Press eBooks
Morris Rosenberg
Over 5,000 high-school students of different social, religious, and national backgrounds were studied to show the effects of family experience, neighborhoods, minority groups, etc. on their self-image and response to so…
A Computational Approach to Edge Detection
29151 citations1986IEEE Transactions on Pattern Analysis and Machine Intelligence
John Canny
This paper describes a computational approach to edge detection. The success of the approach depends on the definition of a comprehensive set of goals for the computation of edge points. These goals must be precise enou…
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
29147 citations2020The Lancet
Fei Zhou, Ting Yu, Ronghui Du, Guohui Fan, Ying Liu
Greedy function approximation: A gradient boosting machine.
29138 citations2001The Annals of Statistics
Jerome H. Friedman
Function estimation/approximation is viewed from the perspective of numerical optimization in function space, rather than parameter space. A connection is made between stagewise additive expansions and steepest-descent…
The NCEP/NCAR 40-Year Reanalysis Project
29136 citations1996Bulletin of the American Meteorological Society
Eugenia Kalnay, Masao Kanamitsu, Robert Kistler, William D. Collins, Dennis G. Deaven
The NCEP and NCAR are cooperating in a project (denoted “reanalysis”) to produce a 40-year record of global analyses of atmospheric fields in support of the needs of the research and climate monitoring communities. This…
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
29123 citations1979Analytical Biochemistry
Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi
Clustal W and Clustal X version 2.0
29111 citations2007Bioinformatics
Mark Larkin, Gordon Blackshields, Nigel P. Brown, R. Chenna, Paul McGettigan
SUMMARY: The Clustal W and Clustal X multiple sequence alignment programs have been completely rewritten in C++. This will facilitate the further development of the alignment algorithms in the future and has allowed pro…
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
29063 citations2014International Journal of Cancer
Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers
Estimates of the worldwide incidence and mortality from 27 major cancers and for all cancers combined for 2012 are now available in the GLOBOCAN series of the International Agency for Research on Cancer. We review the s…
Bowling alone: the collapse and revival of American community
29030 citations2000Choice Reviews Online
BOWLING ALONE warns Americans that their stock of social capital, the very fabric of their connections with each other, has been accelerating down. Putnam describes the resulting impoverishment of their lives and commun…
The rat brain in stereotaxic coordinates
28985 citations1983Neuropeptides
Miklós Palkovits
Sample Selection Bias as a Specification Error
28938 citations1979Econometrica
James J. Heckman
Sample selection bias as a specification error This paper discusses the bias that results from using non-randomly selected samples to estimate behavioral relationships as an ordinary specification error or «omitted vari…
QUANTUM ESPRESSO: a modular and open-source software project for quantum simulations of materials
28896 citations2009Journal of Physics Condensed Matter
Paolo Giannozzi, Stefano Baroni, Nicola Bonini, Matteo Calandra, Roberto Car
QUANTUM ESPRESSO is an integrated suite of computer codes for electronic-structure calculations and materials modeling, based on density-functional theory, plane waves, and pseudopotentials (norm-conserving, ultrasoft,…
A Simplex Method for Function Minimization
28883 citations1965The Computer Journal
J. A. Nelder, R. Mead
A method is described for the minimization of a function of n variables, which depends on the comparison of function values at the (n + 1) vertices of a general simplex, followed by the replacement of the vertex with th…
Data mining: concepts and techniques
28877 citations2012Choice Reviews Online
Jiawei Han, Micheline Kamber, Yeshesvini Shirahatti, Smruti Patel, Rohan Sharma
Our ability to generate and collect data has been increasing rapidly. Not only are all of our business, scientific, and government transactions now computerized, but the widespread use of digital cameras, publication to…